The Pharmacogenomics Journal

FIGURE 3

FROM:

Rat survival to anthrax lethal toxin is likely controlled by a single gene

S H Nye, A L Wittenburg, D L Evans, J A O'Connor, R J Roman and H J Jacob

BACK TO ARTICLE

Figure 3.

Figure and tables index
Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, please contact help@nature.com or the author

Survival of macrophages to challenge with anthrax LeTx. Susceptibility of bone-derived macrophages to LeTx was measured in microwells containing approximately 50 000 rat macrophages isolated from the femur of hybrid and progenitor rats. Selected rat strains include those found to either survive (LEW times WKY, WKY) or die (F344 and F344 times WKY) from anthrax LeTx injection. Each assay well contained a saturating amount of PA (1 mug/ml) plus an amount of LF (0–10 000 ng/ml) determined by serial dilution (x axis). Percent viability (y axis) was calculated by dividing the number of live cells (neutral red dye staining) remaining in each well by the number of cells in the wells with only PA (0 ng/ml LF). Means are presented.

Figure and tables index
BACK TO ARTICLE