TABLE OF CONTENTS

Volume 6, Issue 2 (March/April 2006)

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In This Issue

In This Issue FREE

Pharmacogenomics J 6: 77; doi:10.1038/sj.tpj.6500381

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Meeting Reports

Three years of promise, proposals, and progress on optimizing the benefit/risk of medicines: a commentary on the 3rd FDA-DIA-PWG-PhRMA-BIO pharmacogenomics workshop

R A Salerno and L J Lesko

Pharmacogenomics J 6: 78-81; advance online publication, January 10, 2006; doi:10.1038/sj.tpj.6500345

Retrospective validation of genomic biomarkers – what are the questions, challenges and strategies for developing useful relationships to clinical outcomes – workshop summary

S-J Wang, N Cohen, D A Katz, G Ruano, P M Shaw and B Spear

Pharmacogenomics J 6: 82-88; advance online publication, January 10, 2006; doi:10.1038/sj.tpj.6500363

Designing prospective clinical pharmacogenomic (PG) trials: meeting report on drug development strategies to enhance therapeutic decision making

W L Trepicchio, D Essayan, S T Hall, G Schechter, Z Tezak, S J Wang, D Weinreich and R Simon

Pharmacogenomics J 6: 89-94; advance online publication, January 10, 2006; doi:10.1038/sj.tpj.6500344

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Review

Shedding light into the role of BDNF in the pharmacotherapy of Parkinson's disease

F Fumagalli, G Racagni and M A Riva

Pharmacogenomics J 6: 95-104; advance online publication, January 10, 2006; doi:10.1038/sj.tpj.6500360

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Original Articles

Sequence diversity and haplotype structure at the human CYP3A cluster

E E Thompson, H Kuttab-Boulos, L Yang, B A Roe and A Di Rienzo

Pharmacogenomics J 6: 105-114; advance online publication, November 29, 2005; doi:10.1038/sj.tpj.6500347

CYP2A6 polymorphisms are associated with nicotine dependence and influence withdrawal symptoms in smoking cessation

T Kubota, C Nakajima-Taniguchi, T Fukuda, M Funamoto, M Maeda, E Tange, R Ueki, K Kawashima, H Hara, Y Fujio and J Azuma

Pharmacogenomics J 6: 115-119; advance online publication, January 10, 2006; doi:10.1038/sj.tpj.6500348

Apolipoprotein D is associated with long-term outcome in patients with schizophrenia

T Hansen, R P Hemmingsen, A G Wang, L Olsen, S Timm, K Søeby, K D Jakobsen, M Fenger, J Parnas, H B Rasmussen and T Werge

Pharmacogenomics J 6: 120-125; advance online publication, January 10, 2006; doi:10.1038/sj.tpj.6500350

(AAT)n repeat in the cannabinoid receptor gene (CNR1): association with cocaine addiction in an African-Caribbean population

N Ballon, S Leroy, C Roy, M C Bourdel, A Charles-Nicolas, M O Krebs and M F Poirier

Pharmacogenomics J 6: 126-130; advance online publication, November 29, 2005; doi:10.1038/sj.tpj.6500352

cDNA array reveals increased expression of glucose-dependent insulinotropic polypeptide following chronic clozapine treatment: role in atypical antipsychotic drug-induced adverse metabolic effects

S Sondhi, J M Castellano, V Z Chong, R M Rogoza, K J Skoblenick, B A Dyck, J Gabriele, N Thomas, K Ki, Z B Pristupa, A N Singh, D MacCrimmon, P Voruganti, J Foster and R K Mishra

Pharmacogenomics J 6: 131-140; advance online publication, December 13, 2005; doi:10.1038/sj.tpj.6500346

Gene expression analysis in a murine model of allergic asthma reveals overlapping disease and therapy dependent pathways in the lung

M T Follettie, D K Ellis, D D Donaldson, A A Hill, V Diesl, C DeClercq, J P Sypek, A J Dorner and M Wills-Karp

Pharmacogenomics J 6: 141-152; advance online publication, January 10, 2006; doi:10.1038/sj.tpj.6500357

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