TABLE OF CONTENTS

Volume 4, Issue 1 (2004)

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Editorial

PharmGKB: the pharmacogenetics and pharmacogenomics knowledge base FREE

T E Klein and R B Altman

Pharmacogenomics J 4: 1; doi:10.1038/sj.tpj.6500230

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In This Issue

In This Issue FREE

Pharmacogenomics J 4: 2; doi:10.1038/sj.tpj.6500231

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News and Commentary

Re. KC Wilhelmsen, M Schuckit et al (2003): The search for genes related to a low-level response to alcohol determined by alcohol challenges FREE

M Soyka

Pharmacogenomics J 4: 3-4; doi:10.1038/sj.tpj.6500228

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Perspective

Promoting comparative molecular studies in environmental health research: an overview of the comparative toxicogenomics database (CTD) FREE

C J Mattingly, G T Colby, M C Rosenstein, J N Forrest Jr and J L Boyer

Pharmacogenomics J 4: 5-8; doi:10.1038/sj.tpj.6500225

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Review

Protecting communities in pharmacogenetic and pharmacogenomic research FREE

C Weijer and P B Miller

Pharmacogenomics J 4: 9-16; advance online publication, December 2, 2003; doi:10.1038/sj.tpj.6500219

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Original Articles

Multilocus effects of the renin–angiotensin–aldosterone system genes on blood pressure response to a thiazide diuretic FREE

L Frazier, S T Turner, G L Schwartz, A B Chapman and E Boerwinkle

Pharmacogenomics J 4: 17-23; doi:10.1038/sj.tpj.6500215

Evaluation of the carcinogenic effects of furazolidone and its metabolites in two fish species FREE

A Auro, H Sumano, L Ocampo and A Barragán

Pharmacogenomics J 4: 24-28; advance online publication, December 2, 2003; doi:10.1038/sj.tpj.6500216

Association between a G-protein beta3 subunit gene polymorphism and the symptomatology and treatment responses of major depressive disorders FREE

H-J Lee, J-H Cha, B-J Ham, C-S Han, Y-K Kim, S-H Lee, S-H Ryu, R-H Kang, M-J Choi and M-S Lee

Pharmacogenomics J 4: 29-33; advance online publication, December 2, 2003; doi:10.1038/sj.tpj.6500217

CYP3A5 genotype did not impact on nifedipine disposition in healthy volunteers FREE

T Fukuda, S Onishi, S Fukuen, Y Ikenaga, M Ohno, K Hoshino, K Matsumoto, A Maihara, K Momiyama, T Ito, Y Fujio and J Azuma

Pharmacogenomics J 4: 34-39; advance online publication, December 2, 2003; doi:10.1038/sj.tpj.6500218

Warfarin sensitivity related to CYP2C9, CYP3A5, ABCB1 (MDR1) and other factors FREE

M Wadelius, K Sörlin, O Wallerman, J Karlsson, Q-Y Yue, P K E Magnusson, C Wadelius and H Melhus

Pharmacogenomics J 4: 40-48; advance online publication, December 16, 2003; doi:10.1038/sj.tpj.6500220

A Gilbert's syndrome UGT1A1 variant confers susceptibility to tranilast-induced hyperbilirubinemia FREE

T M Danoff, D A Campbell, L C McCarthy, K F Lewis, M H Repasch, A M Saunders, N K Spurr, I J Purvis, A D Roses and C-F Xu

Pharmacogenomics J 4: 49-53; advance online publication, December 2, 2003; doi:10.1038/sj.tpj.6500221

Human cytosolic sulfotransferase database mining: identification of seven novel genes and pseudogenes FREE

R R Freimuth, M Wiepert, C G Chute, E D Wieben and R M Weinshilboum

Pharmacogenomics J 4: 54-65; advance online publication, December 16, 2003; doi:10.1038/sj.tpj.6500223

Role of polymorphisms in MTHFR and MTHFD1 genes in the outcome of childhood acute lymphoblastic leukemia FREE

M Krajinovic, É Lemieux-Blanchard, S Chiasson, M Primeau, I Costea and A Moghrabi

Pharmacogenomics J 4: 66-72; advance online publication, December 2, 2003; doi:10.1038/sj.tpj.6500224

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