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2001, Volume 1, Number 1

Table of Contents

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Editorial
Welcome to The Pharmacogenomics Journal FREE
Julio Licinio MD
Abstract  |  Full text  |  PDF 1
In This Issue FREE
Abstract  |  Full text  |  PDF 3
News and Commentaries
The molecular dissection of human diseases after the human genome project FREE
L Peltonen
Abstract  |  Full text  |  PDF 5
Postgenomic prospects of success in drug development and pharmacotherapy FREE
A Rane
Abstract  |  Full text  |  PDF 6
Sudden impact? The human genome sequence and the pace of gene discovery in complex diseases FREE
D A Collier
Abstract  |  Full text  |  PDF 9
Significance of the human genome sequence to drug discovery FREE
O Grenet
Abstract  |  Full text  |  PDF 11
The C/At is out of the bag: a gene for mental illness FREE
M-L Wong
Abstract  |  Full text  |  PDF 13
Perspectives
Large-scale proteomics and its future impact on medicine FREE
G L Corthals & P S Nelson
Abstract  |  Full text  |  PDF 15
Pharmacogenomics, ethnicity, and susceptibility genes FREE
D W Nebert & A G Menon
Abstract  |  Full text  |  PDF 19
EELS (Ethical, Economic, Legal & Social) Article
Pharmacogenetics and the future of medical practice: conceptual considerations FREE
K Lindpaintner
Abstract  |  Full text  |  PDF 23
Clinical Implication
The pharmacogenetics of asthma: a candidate gene approach FREE
E S Silverman, S B Liggett, E W Gelfand, L J Rosenwasser, R M Baron, S Bolk, S T Weiss & J M Drazen
Abstract  |  Full text  |  PDF 27
Reviews
Site-specific molecular design and its relevance to pharmacogenomics and chemical biology FREE
D Bailey, E Zanders & P Dean
Abstract  |  Full text  |  PDF 38
The use of animal models in expression pharmacogenomic analyses FREE
B E Gould Rothberg
Abstract  |  Full text  |  PDF 48
Polymorphisms in the ABC drug transporter gene MDR1 FREE
U Brinkmann & M Eichelbaum
Abstract  |  Full text  |  PDF 59
Original Articles
Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy FREE
S T Pullarkat, J Stoehlmacher, V Ghaderi, Y-P Xiong, S A Ingles, A Sherrod, R Warren, D Tsao-Wei, S Groshen & H-J Lenz
Abstract  |  Full text  |  PDF 65
Serotonin transporter gene associated with lithium prophylaxis in mood disorders FREE
A Serretti, R Lilli, L Mandelli, C Lorenzi & E Smeraldi
Abstract  |  Full text  |  PDF 71
G649, an allelic variant of the human H2 receptor with low basal activity, is resistant to upregulation upon antagonist exposure FREE
Y Fukushima, T Saitoh, M Anai, K Tsukuda, Y Onishi, H Sakoda, K Inukai, T Ogihara, M Funaki, H Ono, M Fujishiro, T Ishikawa, R Nagai, M Omata & T Asano
Abstract  |  Full text  |  PDF 78
2001, Volume 1, Number 1
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