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Article |
Genome-wide meta-analysis of variant-by-diuretic interactions as modulators of lipid traits in persons of European and African ancestry
- L. de las Fuentes
- , Y. J. Sung
- , C. M. Sitlani
- , C. L. Avery
- , T. M. Bartz
- , C. de Keyser
- , D. S. Evans
- , X. Li
- , S. K. Musani
- , R. Ruiter
- , A. V. Smith
- , F. Sun
- , S. Trompet
- , H. Xu
- , D. K. Arnett
- , J. C. Bis
- , U. Broeckel
- , E. L. Busch
- , Y.-D. I. Chen
- , A. Correa
- , S. R. Cummings
- , J. S. Floyd
- , I. Ford
- , X. Guo
- , T. B. Harris
- , M. A. Ikram
- , L. Lange
- , L. J. Launer
- , A. P. Reiner
- , K. Schwander
- , N. L. Smith
- , N. Sotoodehnia
- , J. D. Stewart
- , D. J. Stott
- , T. Stürmer
- , K. D. Taylor
- , A. Uitterlinden
- , R. S. Vasan
- , K. L. Wiggins
- , L. A. Cupples
- , V. Gudnason
- , S. R. Heckbert
- , J. W. Jukema
- , Y. Liu
- , B. M. Psaty
- , D. C. Rao
- , J. I. Rotter
- , B. Stricker
- , J. G. Wilson
- & E. A. Whitsel
-
Article |
Genetic contribution to lipid target achievement with statin therapy: a prospective study
- Cristina Ruiz-Iruela
- , Beatriz Candás-Estébanez
- , Xavier Pintó-Sala
- , Neus Baena-Díez
- , Assumpta Caixàs-Pedragós
- , Roser Güell-Miró
- , Rosa Navarro-Badal
- , Pilar Calmarza
- , Jose Luis Puzo-Foncilla
- , Pedro Alía-Ramos
- & Ariadna Padró-Miquel
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Article |
Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian randomization study
- Roelof A. J. Smit
- , Stella Trompet
- , Aaron Leong
- , Mark O. Goodarzi
- , Iris Postmus
- , Helen Warren
- , Elizabeth Theusch
- , Michael R. Barnes
- , Benoit J. Arsenault
- , Xiaohui Li
- , QiPing Feng
- , Daniel I. Chasman
- , L. Adrienne Cupples
- , Graham A. Hitman
- , Ronald M. Krauss
- , Bruce M. Psaty
- , Jerome I. Rotter
- , Saskia le Cessie
- , C. Michael Stein
- & J. Wouter Jukema
-
Article |
Prospective validation of the International Warfarin Pharmacogenetics Consortium algorithm in high-risk elderly people (VIALE study)
- Amelia Filippelli
- , Simona Signoriello
- , Ciro Bancone
- , Graziamaria Corbi
- , Valentina Manzo
- , Severino Iesu
- , Cecilia Politi
- , Alberto Gigantino
- , Maria Teresa De Donato
- , Paolo Masiello
- , Vittorio Simeon
- , Alessandro Della Corte
- , Michele Cellurale
- , Valeria Conti
- , Massimo Frigino
- , Tiziana Ciarambino
- , Marta Marracino
- , Laura Carpenito
- , Nicola Ferrara
- , Marisa De Feo
- & Ciro Gallo
-
Review Article |
Opportunities for pharmacists to integrate pharmacogenomics into clinical practice
- Yan-Ting Wang
- , Man Yee Merl
- , Jun Yang
- , Zhi-Xiang Zhu
- & Guo-Hui Li
-
Article |
HLA-A*02:01 allele is associated with tanshinone-induced cutaneous drug reactions in Chinese population
- Qinyuan Zhu
- , Yanzhou Zhang
- , Jiekun Xuan
- , Fanping Yang
- , Binbin Du
- , Sheng-an Chen
- , Sijia Yan
- , Menglin Jiang
- , Huizhong Zhu
- , Hao Xiong
- , Xiaoqun Luo
- & Qinghe Xing
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Article |
Association between serotonin 2A receptor (HTR2A), serotonin transporter (SLC6A4) and brain-derived neurotrophic factor (BDNF) gene polymorphisms and citalopram/sertraline induced sexual dysfunction in MDD patients
- Merve Demirbugen Oz
- , Bora Baskak
- , Zuhal Uckun
- , Nazan Yuce Artun
- , Hatice Ozdemir
- , Tugba Kizil Ozel
- , Halise Devrimci Ozguven
- & H. Sinan Suzen
-
Article |
Genetic and clinical prediction models for the efficacy and hepatotoxicity of methotrexate in patients with rheumatoid arthritis: a multicenter cohort study
- Akira Onishi
- , Shigeo Kamitsuji
- , Miwa Nishida
- , Yuko Uemura
- , Miho Takahashi
- , Toshiharu Saito
- , Yuichiro Yoshida
- , Masaki Kobayashi
- , Mizuho Kawate
- , Keisuke Nishimura
- , Kenta Misaki
- , Yumiko Nobuhara
- , Takashi Nakazawa
- , Saori Hatachi
- , Goh Tsuji
- , Akio Morinobu
- & Shunichi Kumagai
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Article |
Association between endothelial nitric oxide synthase (NOS3) rs2070744 and the risk for migraine
- Elena García-Martín
- , Santiago Navarro-Muñoz
- , Christopher Rodriguez
- , Mercedes Serrador
- , Hortensia Alonso-Navarro
- , Marisol Calleja
- , Laura Turpín-Fenoll
- , Marta Recio-Bermejo
- , Rafael García-Ruiz
- , Jorge Millán-Pascual
- , Francisco Navacerrada
- , José Francisco Plaza-Nieto
- , Esteban García-Albea
- , José A. G. Agúndez
- & Félix Javier Jiménez-Jiménez
-
Review Article
| Open AccessDrug–drug–gene interactions and adverse drug reactions
- Mustafa Adnan Malki
- & Ewan Robert Pearson
-
Article |
PACSIN2 rs2413739 influence on thiopurine pharmacokinetics: validation studies in pediatric patients
- Raffaella Franca
- , Gabriele Stocco
- , Diego Favretto
- , Nagua Giurici
- , Irene del Rizzo
- , Franco Locatelli
- , Luciana Vinti
- , Andrea Biondi
- , Antonella Colombini
- , Franca Fagioli
- , Elena Barisone
- , Marco Pelin
- , Stefano Martellossi
- , Alessandro Ventura
- , Giuliana Decorti
- & Marco Rabusin
-
Article
| Open AccessPharmacogenomic biomarker information differences between drug labels in the United States and Hungary: implementation from medical practitioner view
- Reka Varnai
- , Istvan Szabo
- , Greta Tarlos
- , Laszlo Jozsef Szentpeteri
- , Attila Sik
- , Sandor Balogh
- & Csilla Sipeky
-
Article
| Open AccessMeta-analytic method reveal a significant association of theBDNF Val66Met variant with smoking persistence based on a large samples
- Hailong Zhao
- , Shuicai Xiong
- , Zhiwei Li
- , Xuebiao Wu
- & Lijuan Li
-
Article |
Association of polymorphisms in leptin and adiponectin genes with long-term outcomes in renal transplant recipients
- Guillermo Gervasini
- , Guadalupe García-Pino
- , Sonia Mota-Zamorano
- , Enrique Luna
- , Montserrat García-Cerrada
- , María Ángeles Tormo
- & Juan José Cubero
-
Review Article |
Ketamine in seizure management and future pharmacogenomic considerations
- Giovanna Soldatelli Borsato
- , Jason L. Siegel
- , Mariah Q. Rose
- , Michelle Ojard
- , Anteneh Feyissa
- , Alfredo Quinones-Hinojosa
- , Daniel A. Jackson
- , Emily R. Rogers
- & William D. Freeman
-
Article |
Gender based differences, pharmacogenetics and adverse events in chronic pain management
- Beatriz Planelles
- , César Margarit
- , María-del-Mar Inda
- , Pura Ballester
- , Javier Muriel
- , Jordi Barrachina
- , Raquel Ajo
- , María-Dolores Esteban
- & Ana M Peiró
-
Article |
CYP2C9, VKORC1, and CYP4F2 polymorphisms and pediatric warfarin maintenance dose: a systematic review and meta-analysis
- Masanobu Takeuchi
- , Tohru Kobayashi
- , Tina Biss
- , Farhad Kamali
- , Susan I. Vear
- , Richard H. Ho
- , Fanny Bajolle
- , Marie-Anne Loriot
- , Kaitlyn Shaw
- , Bruce C. Carleton
- , Anna-Karin Hamberg
- , Mia Wadelius
- , Keiichi Hirono
- , Masato Taguchi
- , Takuya Wakamiya
- , Masakatsu Yanagimachi
- , Keita Hirai
- , Kunihiko Itoh
- , Leonardo R. Brandão
- & Shinya Ito
-
Article |
Genetic variation of cisplatin-induced ototoxicity in non-cranial-irradiated pediatric patients using a candidate gene approach: The International PanCareLIFE Study
- Eva Clemens
- , Linda Broer
- , Thorsten Langer
- , André G. Uitterlinden
- , Andrica C. H. de Vries
- , Martine van Grotel
- , Saskia F. M. Pluijm
- , Harald Binder
- , Julianne Byrne
- , Eline van Dulmen-den Broeder
- , Marco Crocco
- , Desiree Grabow
- , Peter Kaatsch
- , Melanie Kaiser
- , Line Kenborg
- , Jeanette F. Winther
- , Catherine Rechnitzer
- , Henrik Hasle
- , Tomas Kepak
- , Anne-Lotte F. van der Kooi
- , Leontien C. Kremer
- , Jarmila Kruseova
- , Claudia E. Kuehni
- , Heleen van der Pal
- , Ross Parfitt
- , Dirk Deuster
- , Peter Matulat
- , Claudia Spix
- , Amelie Tillmanns
- , Wim J. E. Tissing
- , Lara Maier
- , Antoinette am Zehnhoff-Dinnesen
- , Oliver Zolk
- , Marry M. van den Heuvel-Eibrink
- , P. Kaatsch
- , D. Grabow
- , J. Byrne
- , H. Campbell
- , K. O’Brien
- , L. C. M. Kremer
- , T. Langer
- , E. van Dulmen-den Broeder
- , M. H. van den Berg
- , M. M. van den Heuvel-Eibrink
- , A. Borgmann-Staudt
- , A. am Zehnhoff-Dinnesen
- , C. E. Kuehni
- , R. Haupt
- , T. Kepak
- , C. Berger
- , J. F. Winther
- , J. Kruseova
- , G. Calaminus
- , K. Baust
- & U. Dirksen
-
Article |
Polymorphisms of NF-κB pathway genes influence adverse drug reactions of gefitinib in NSCLC patients
- Shuang Xin
- , Yuanyuan Zhao
- , Changzheng Wang
- , Yan Huang
- , Wei Zhuang
- , Yuxiang Ma
- , Min Huang
- , Xun Xu
- , Xueding Wang
- & Li Zhang
-
Article |
The effect of genetic and nongenetic factors on warfarin dose variability in Qatari population
- Loulia Bader
- , Ahmad Mahfouz
- , Mohammed Kasem
- , Shaban Mohammed
- , Sumayya Alsaadi
- , Osama Abdelsamad
- , Rasha Elenani
- , Ezeldin Soaly
- , Abdelnasser Elzouki
- , Nasser Rizk
- , Sherief Khalifa
- , Mohamed H. Shahin
- , Larisa H. Cavallari
- , Fatima Mraiche
- & Hazem Elewa
-
Article |
The efficacy of interferon-beta therapy in multiple sclerosis patients: investigation of the RORA gene as a predictive biomarker
- Seyed Abdulmajid Ayatollahi
- , Soudeh Ghafouri-Fard
- , Mohammad Taheri
- & Rezvan Noroozi
-
Article |
Meta-analysis of the associations of CYP2B6-516G>T polymorphisms with efavirenz-induced central nervous system side effects and virological outcome in HIV-infected adults
- Lin Cheng
- , Yu Wang
- , Xiaoyu Li
- , Wei Feng
- , Bangbi Weng
- , Qian Yuan
- , Peiyuan Xia
- & Fengjun Sun
-
Article |
A functional HTR1A polymorphism, rs6295, predicts short-term response to lurasidone: confirmation with meta-analysis of other antipsychotic drugs
- Akane Yoshikawa
- , Jiang Li
- & Herbert Y. Meltzer
-
Article |
Influence of CYP2B6 activity score on the pharmacokinetics and safety of single dose efavirenz in healthy volunteers
- Pablo Zubiaur
- , Miriam Saiz-Rodríguez
- , Dolores Ochoa
- , Carmen Belmonte
- , Manuel Román
- , Gina Mejía
- , Samuel Martín-Vilchez
- & Francisco Abad-Santos
-
Article |
ABCB1 single-nucleotide variants and survival in patients with glioblastoma treated with radiotherapy concomitant with temozolomide
- Annika Malmström
- , Malgorzata Łysiak
- , Lisa Åkesson
- , Ingrid Jakobsen
- , Munila Mudaisi
- , Peter Milos
- , Martin Hallbeck
- , Victoria Fomichov
- , Helle Broholm
- , Kirsten Grunnet
- , Hans Skovgaard Poulsen
- , Charlotte Bratthäll
- , Michael Strandeus
- , Angeliki Papagiannopoulou
- , Marie Stenmark-Askmalm
- , Henrik Green
- & Peter Söderkvist
-
Review Article |
Predictive genetic biomarkers for the efficacy of methotrexate in rheumatoid arthritis: a systematic review
- Frank Eektimmerman
- , Jesse J. Swen
- , Moenira B. Madhar
- , Cornelia F. Allaart
- & Henk-Jan Guchelaar
-
Article |
Dissecting the m6A methylation affection on afatinib resistance in non-small cell lung cancer
- Qianqian Meng
- , Shuyuan Wang
- , Shunheng Zhou
- , Haizhou Liu
- , Xueyan Ma
- , Xu Zhou
- , Hui Liu
- , Chaohan Xu
- & Wei Jiang
-
Article |
Pharmacogenetic interactions in amyotrophic lateral sclerosis: a step closer to a cure?
- Ruben P. A. van Eijk
- , Marinus J. C. Eijkemans
- , Stavros Nikolakopoulos
- , Marc D. Jansen
- , Henk-Jan Westeneng
- , Kristel R. van Eijk
- , Rick A. A. van der Spek
- , Joke J. F. A. van Vugt
- , Sanne Piepers
- , Geert-Jan Groeneveld
- , Jan H. Veldink
- , Leonard H. van den Berg
- & Michael A. van Es
-
Article |
Pharmacogenetic determinants of kidney-associated urinary and serum abnormalities in antiretroviral-treated HIV-positive patients
- Jessica Cusato
- , Andrea Calcagno
- , Letizia Marinaro
- , Valeria Avataneo
- , Antonio DʹAvolio
- , Giovanni Di Perri
- & Stefano Bonora
-
Consensus Statement |
Pharmacogenomics, biomarker network, and allele frequencies in colorectal cancer
- Andrés López-Cortés
- , César Paz-y-Miño
- , Santiago Guerrero
- , Gabriela Jaramillo-Koupermann
- , Ángela León Cáceres
- , Dámaris P. Intriago-Baldeón
- , Jennyfer M. García-Cárdenas
- , Patricia Guevara-Ramírez
- , Isaac Armendáriz-Castillo
- , Paola E. Leone
- , Luis Abel Quiñones
- , Juan Pablo Cayún
- & Néstor W. Soria
-
Review Article |
Challenges to assess substrate-dependent allelic effects in CYP450 enzymes and the potential clinical implications
- Lauren A. Marcath
- , Amy L. Pasternak
- & Daniel L. Hertz
-
Article |
Impact of CYP1A2, CYP2C19, and CYP2D6 genotype- and phenoconversion-predicted enzyme activity on clozapine exposure and symptom severity
- Dorothea Lesche
- , Sam Mostafa
- , Ian Everall
- , Christos Pantelis
- & Chad A. Bousman
-
Article |
Genes and variants in hematopoiesis-related pathways are associated with gemcitabine/carboplatin-induced thrombocytopenia
- Niclas Björn
- , Benjamín Sigurgeirsson
- , Anna Svedberg
- , Sailendra Pradhananga
- , Eva Brandén
- , Hirsh Koyi
- , Rolf Lewensohn
- , Luigi de Petris
- , Maria Apellániz-Ruiz
- , Cristina Rodríguez-Antona
- , Joakim Lundeberg
- & Henrik Gréen
-
Article |
Genetic and epigenetic polymorphisms of eNOS and CYP2D6 in mainland Chinese Tibetan, Mongolian, Uygur, and Han populations
- Guangzhao Qi
- , Shengju Yin
- , Guoliang Zhang
- & Xin Wang
-
Consensus Statement |
Folyl polyglutamate synthethase (FPGS) gene polymorphisms may influence methotrexate adverse events in South Indian Tamil Rheumatoid Arthritis patients
- Niveditha Muralidharan
- , Rajan Sundaram
- , Sunitha Kodidela
- , K. G. Chengappa
- , Christina Mary Mariaselvam
- , Durga P. Misra
- & Vir S. Negi
-
Editorial |
Analysis of galanin receptor GALR2 in multiple sclerosis
- Mary Encarnacion
- , Cecily Q. Bernales
- , Anthony L. Traboulsee
- , A. Dessa Sadovnick
- & Carles Vilariño-Güell
-
Article |
A GALNT14 rs9679162 genotype-guided therapeutic strategy for advanced hepatocellular carcinoma: systemic or hepatic arterial infusion chemotherapy
- Chen-Chun Lin
- , Chao-Wei Hsu
- , Yi-Cheng Chen
- , Ming-Ling Chang
- , Kung-Hao Liang
- , Ming-Wei Lai
- , Chih-Lang Lin
- , Rong-Nan Chien
- , Kwang-Huei Lin
- & Chau-Ting Yeh
-
Article
| Open AccessTowards precision medicine: interrogating the human genome to identify drug pathways associated with potentially functional, population-differentiated polymorphisms
- Maulana Bachtiar
- , Brandon Nick Sern Ooi
- , Jingbo Wang
- , Yu Jin
- , Tin Wee Tan
- , Samuel S. Chong
- & Caroline G. L. Lee
-
Article |
Pharmacogenomic genotypes define genetic ancestry in patients and enable population-specific genomic implementation
- Wenndy Hernandez
- , Keith Danahey
- , Xun Pei
- , Kiang-Teck J. Yeo
- , Edward Leung
- , Samuel L. Volchenboum
- , Mark J. Ratain
- , David O. Meltzer
- , Barbara E. Stranger
- , Minoli A. Perera
- & Peter H. O’Donnell
-
Article |
Human H1 receptor (HRH1) gene polymorphism is associated with the severity of side effects after desloratadine treatment in Chinese patients with chronic spontaneous uticaria
- Juan Li
- , Wangqing Chen
- , Cong Peng
- , Wu Zhu
- , Zhaoqian Liu
- , Wei Zhang
- , Juan Su
- , Jie Li
- & Xiang Chen
-
Perspective |
Concerns regarding use of patient-reported outcomes in biomarker studies of chemotherapy-induced peripheral neuropathy
- Daniel L. Hertz
-
Article |
Algorithm for predicting low maintenance doses of warfarin using age and polymorphisms in genes CYP2C9 and VKORC1 in Brazilian subjects
- Aline de Oliveira Magalhães Mourão
- , Karina Braga Gomes
- , Edna Afonso Reis
- , Renan Pedra de Souza
- , Emílio Itamar de Freitas Campos
- , Daniel Dias Ribeiro
- , Manoel Otávio da Costa Rocha
- & Maria Auxiliadora Parreiras Martins
-
Article |
HLA-DRB1*07:01 and lapatinib-induced hepatotoxicity: a systematic review and meta-analysis
- Wimonchat Tangamornsuksan
- , Chuenjid Kongkaew
- , C. N. Scholfield
- , Suphat Subongkot
- & Manupat Lohitnavy
-
Article |
Cost-effectiveness analysis of multigene expression profiling assays to guide adjuvant therapy decisions in women with invasive early-stage breast cancer
- Malek B. Hannouf
- , Gregory S. Zaric
- , Phillip Blanchette
- , Christine Brezden-Masley
- , Mike Paulden
- , Christopher McCabe
- , Jacques Raphael
- & Muriel Brackstone
-
Article |
Genetic association between CD96 locus and immunogenicity to anti-TNF therapy in Crohn’s disease
- Adrià Aterido
- , Núria Palau
- , Eugeni Domènech
- , Pilar Nos Mateu
- , Ana Gutiérrez
- , Fernando Gomollón
- , Juan L. Mendoza
- , Esther Garcia-Planella
- , Manuel Barreiro-de Acosta
- , Fernando Muñoz
- , Maribel Vera
- , Cristina Saro
- , Maria Esteve
- , Montserrat Andreu
- , María Chaparro
- , Julián Panés
- , Valle García-Sánchez
- , María López-Lasanta
- , Andrea Pluma
- , Laia Codó
- , Andrés García-Montero
- , Josep Manyé
- , Javier P. Gisbert
- , Sara Marsal
- & Antonio Julià
-
Article |
Impact of SLCO1B3 polymorphisms on clinical outcomes in lung allograft recipients receiving mycophenolic acid
- Laneshia K. Tague
- , Derek E. Byers
- , Ramsey Hachem
- , Daniel Kreisel
- , Alexander S. Krupnick
- , Hrishikesh S. Kulkarni
- , Catherine Chen
- , Howard J. Huang
- & Andrew Gelman
-
Article |
Identification of SAMD9L as a susceptibility locus for intravenous immunoglobulin resistance in Kawasaki disease by genome-wide association analysis
- Jae-Jung Kim
- , Sin Weon Yun
- , Jeong Jin Yu
- , Kyung Lim Yoon
- , Kyung-Yil Lee
- , Hong-Ryang Kil
- , Gi Beom Kim
- , Myung-Ki Han
- , Min Seob Song
- , Hyoung Doo Lee
- , Kee Soo Ha
- , Sejung Sohn
- , Ryota Ebata
- , Hiromichi Hamada
- , Hiroyuki Suzuki
- , Kaoru Ito
- , Yoshihiro Onouchi
- , Young Mi Hong
- , Gi Young Jang
- , Jong-Keuk Lee
- , Jeong Jin Yu
- , In-Sook Park
- , Soo-Jong Hong
- , Kwi-Joo Kim
- , Jong-Keuk Lee
- , Jae-Jung Kim
- , Young Mi Hong
- , Sejung Sohn
- , Gi Young Jang
- , Kee Soo Ha
- , Hyo-Kyoung Nam
- , Jung-Hye Byeon
- , Sin Weon Yun
- , Myung-Ki Han
- , Kyung-Yil Lee
- , Ja-Young Hwang
- , Jung-Woo Rhim
- , Min Seob Song
- , Hyoung Doo Lee
- , Dong Soo Kim
- , Kyung Lim Yoon
- , Hong-Ryang Kil
- , Gi Beom Kim
- , Jae-Moo Lee
- & Jong-Duk Kim
-
Article |
A genome-wide association study of tramadol metabolism from post-mortem samples
- Frank R. Wendt
- , Anna-Liina Rahikainen
- , Jonathan L. King
- , Antti Sajantila
- & Bruce Budowle
-
Article |
Prognostic impact of genetic variants of CYP19A1 and UGT2B17 in a randomized trial for endocrine-responsive postmenopausal breast cancer
- Harriet Johansson
- , Valentina Aristarco
- , Sara Gandini
- , Jennifer Gjerde
- , Debora Macis
- , Aliana Guerrieri-Gonzaga
- , Davide Serrano
- , Matteo Lazzeroni
- , Agnita Rajasekaran
- , Clark V Williard
- , Gunnar Mellgren
- , Andrea DeCensi
- & Bernardo Bonanni
