Vasculitis syndromes

Definition

Vasculitis sydromes are a group of autoimmune disorders characterized by inflammation of the blood vessels, either primary or secondary to another condition. The different vasculitis syndromes are classified by the size of blood vessel predominantly affected.

Latest Research and Reviews

  • Reviews |

    Nonsystemic vasculitic neuropathy (NSVN) is an under-recognized single-organ vasculitis of peripheral nerves. In this Review, Collins and Hadden provide an update on the classification, diagnosis and treatment of NSVN, and propose definitions and an up-to-date differential diagnosis of multifocal neuropathy.

    • Michael P. Collins
    •  & Robert D. Hadden
  • Reviews |

    Accumulating evidence indicates that activation of the complement system is crucial for the development of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). This Review provides an overview of the role of complement activation in AAV, and discusses how targeting this pathway can provide opportunities for treatment.

    • Min Chen
    • , David R. W. Jayne
    •  & Ming-Hui Zhao
  • Research | | open

    • F. David Carmona
    • , Patrick Coit
    • , Güher Saruhan-Direskeneli
    • , José Hernández-Rodríguez
    • , María C. Cid
    • , Roser Solans
    • , Santos Castañeda
    • , Augusto Vaglio
    • , Haner Direskeneli
    • , Peter A. Merkel
    • , Luigi Boiardi
    • , Carlo Salvarani
    • , Miguel A. González-Gay
    • , Javier Martín
    • , Amr H. Sawalha
    • , Spanish GCA Study Group
    • , Agustín Martínez-Berriochoa
    • , Ainhoa Unzurrunzaga
    • , Ana Hidalgo-Conde
    • , Ana Belén Madroñero Vuelta
    • , Antonio Fernández-Nebro
    • , M. Carmen Ordóñez-Cañizares
    • , Benjamín Fernández-Gutiérrez
    • , Luis Rodríguez-Rodríguez
    • , Begoña Escalante
    • , Begoña Marí-Alfonso
    • , Bernardo Sopeña
    • , Carmen Gómez-Vaquero
    • , Enrique Raya
    • , Elena Grau
    • , José A. Román
    • , Esther F. Vicente
    • , Eugenio de Miguel
    • , Francisco J. López-Longo
    • , Lina Martínez
    • , Inmaculada C. Morado
    • , J. Bernardino Díaz-López
    • , Luis Caminal-Montero
    • , Aleida Martínez-Zapico
    • , Javier Narváez
    • , Jordi Monfort
    • , Laura Tío
    • , José A. Miranda-Filloy
    • , Julio Sánchez-Martín
    • , Juan J. Alegre-Sancho
    • , Luis Sáez-Comet
    • , Mercedes Pérez-Conesa
    • , Marc Corbera-Bellalta
    • , Marc Ramentol-Sintas
    • , María Jesús García-Villanueva
    • , Mercedes Guijarro Rojas
    • , Norberto Ortego-Centeno
    • , Raquel Ríos Fernández
    • , José Luis Callejas
    • , Olga Sanchez Pernaute
    • , Patricia Fanlo Mateo
    • , Ricardo Blanco
    • , Sergio Prieto-González
    • , Víctor Manuel Martínez-Taboada
    • , Italian GCA Study Group
    • , Alessandra Soriano
    • , Claudio Lunardi
    • , Davide Gianfreda
    • , Daniele Santilli
    • , Francesco Bonatti
    • , Francesco Muratore
    • , Giulia Pazzola
    • , Olga Addimanda
    • , Giacomo Emmi
    • , Giuseppe A. Ramirez
    • , Lorenzo Beretta
    • , Marcello Govoni
    • , Marco A. Cimmino
    • , Turkish Takayasu Study Group
    • , Ahmet Mesut Onat
    • , Ayse Cefle
    • , Ayten Yazici
    • , Bünyamin Kısacık
    • , Ediz Dalkilic
    • , Emire Seyahi
    • , Izzet Fresko
    • , Ercan Tunc
    • , Eren Erken
    • , Hüseyin TE Ozer
    • , Kenan Aksu
    • , Gokhan Keser
    • , Mehmet A. Ozturk
    • , Muge Bıcakcıgil
    • , Nurşen Duzgun
    • , Omer Karadag
    • , Sedat Kiraz
    • , Ömer N. Pamuk
    • , Servet Akar
    • , Fatos Onen
    • , Nurullah Akkoc
    • , Sevil Kamali
    • , Murat Inanc
    • , Sibel P. Yentür
    • , Sibel Z. Aydin
    • , Fatma Alibaz-Oner
    • , Curry L. Koening
    • , Carol A. Langford
    • , Paul A. Monach
    • , Christian Pagnoux
    • , Sharon A. Chung
    • , Vasculitis Clinical Research Consortium
    • , Larry Moreland
    • , Nader A. Khalidi
    • , Simon Carette
    • , Kenneth J. Warrington
    • , Yasar Karaaslan
    • , Philip Seo
    • , Robert Spiera
    • , David Cuthbertson
    • , Timuçin Kaşifoğlu
    • , Zeynep Ozbalkan
    • , Gary S. Hoffman
    • , Veli Cobankara
    • , Carol A. McAlear
    • , Steven R. Ytterberg
    • , Lindsay J. Forbess
    • , Antoine G. Sreih
    • , Askin Ates
    •  & Kathleen McKinnon-Maksimowicz
  • Reviews |

    Systemic vasculitides can involve the gastrointestinal tract, hepatic system and pancreas, causing a range of gastrointestinal manifestations. In this Review, the authors summarize the epidemiology, gastrointestinal manifestations and management of systemic vasculitides as well as single-organ vasculitides in the gastrointestinal tract.

    • Medha Soowamber
    • , Adam V. Weizman
    •  & Christian Pagnoux

News and Comment