Urinary tract infection

A urinary tract infection is any microbial invasion that results in an inflammatory response in the epithelium of the urinary tract.

Latest Research and Reviews

News and Comment

  • Comments and Opinion |

    Diagnosis of urinary tract infection (UTI) includes anatomical distinctions because the severity of infection and treatment decisions depend on the infected organ; however, bacterial prostatitis is usually absent from discussions regarding UTI. By considering bacterial prostatitis a UTI, we can increase understanding of the pathogenesis and immune response in the prostate to develop improved therapeutics.

    • Federico Lupo
    •  & Molly A. Ingersoll
  • Comments and Opinion |

    Since the discovery and confirmation of the human urobiome, highly influential studies to characterize this microbial community and understand how it relates to human health and disease have been undertaken. Technological advances will improve information about the status of the urobiome for clinicians.

    • Alan J. Wolfe
    •  & Linda Brubaker
  • News and Views |

    Applying the principles of ‘omics’ to urinary tract infection opens up exciting diagnostic and management avenues. Urinary cell-free DNA can be used to gain new insight not only into the spectrum of pathogens present in host urine but also their likelihood to cause disease.

    • Rhana Hassan Zakri
    •  & Jonathon Olsburgh
  • News and Views |

    The detection of 78 bacterial species in the urinary tracts of 77 catheterized female patients further emphasizes that the urinary tract is not sterile. However, many questions arise from these findings, not the least of which is what these organisms are doing in the urinary tract.

    • Gregor Reid