Transcriptional regulatory elements
Transcriptional regulatory elements are nucleotide sequences of a gene that are involved in regulation of genetic transcription. These include the promoter, plus response elements, activator and enhancer sequences for binding of transcription factors to aid RNA polymerase binding and promote expression, and operator or silencer sequences to which repressor proteins bind to block RNA polymerase attachment and prevent expression.
Latest Research and Reviews
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Functional genomics reveal gene regulatory mechanisms underlying schizophrenia risk
Nature Communications 10, 670 -
Research | | open
Integrator is a key component of human telomerase RNA biogenesis
Scientific Reports 9, 1701 -
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Synergistic activation of the NEU4 promoter by p73 and AP2 in colon cancer cells
Scientific Reports 9, 950
Regulation of miRNAs by Snail during epithelial-to-mesenchymal transition in HT29 colon cancer cells
Functional genomics reveal gene regulatory mechanisms underlying schizophrenia risk
Integrator is a key component of human telomerase RNA biogenesis
Notch signaling facilitates hepatitis B virus covalently closed circular DNA transcription via cAMP response element-binding protein with E3 ubiquitin ligase-modulation
PpERF3 positively regulates ABA biosynthesis by activating PpNCED2/3 transcription during fruit ripening in peach
Synergistic activation of the NEU4 promoter by p73 and AP2 in colon cancer cells
Enhancers and promoters regulate burst kinetics
Quantitative integration of epigenomic variation and transcription factor binding using MAmotif toolkit identifies an important role of IRF2 as transcription activator at gene promoters
The power of 3′ UTRs
Gene expression: Developmental enhancers in action
Gene expression: Developmental enhancers in action
Gene expression: The yin and yang of enhancer–promoter interactions