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Tissue engineering is a set of methods that can replace or repair damaged or diseased tissues with natural, synthetic, or semisynthetic tissue mimics. These mimics can either be fully functional or will grow into the required functionality.
Angiogenesis has been implicated in fibrotic diseases of the liver. Here, the authors developed microniches that mimic angiogenesis during different stages of liver fibrosis, and demonstrate the role of mechanotransduction in fibrogenesis.
Regenerative medicine can be viewed as 'tissue engineering V2.0'. Discoveries and novel applications of technology advanced the field considerably in 2016, with the use of new biomaterials, stem cells and biologically active molecules.