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The striate cortex is the part of the visual cortex that is involved in processing visual information. The striate cortex is the first cortical visual area that receives input from the lateral geniculate nucleus in the thalamus.
Mapping the organization of excitatory inputs onto the dendritic spines of individual mouse visual cortex neurons reveals how inputs representing features from the extended visual scene are organized and establishes a computational unit suited to amplify contours and elongated edges.
Neural processing speed slows with age, but the relationship between this slowing and brain atrophy is unknown. Here, authors show that age-related functional brain differences in auditory and visual processing are partly due to structural differences in the distinct brain regions underlying these processes.
Single-cell characterization and perturbation of neurons is critical for revealing the structure-function relationship of brain cells. Here the authors develop a robot that performs single-cell electroporation and extracellular electrophysiology and can be used for performing in vivo single-cell experiments in deep brain tissues optically difficult to access.
The authors establish a critical role for somatostatin interneurons in visually induced gamma oscillations in the primary visual cortex of mice. Optogenetic manipulations in awake animals, combined with an innovative computational model with multiple interneuron subtypes, provide a mechanism for the synchronization of neural firing across the retinotopic map.
Orientation selectivity in visual cortex is not simply the result of linear input summation. Instead, selectivity is enhanced by nonlinear dendritic transformation of spatially clustered, cotuned synaptic inputs.
Homeostatic mechanisms that maintain the firing rate of neurons in the visual cortex of rats within a stable range occur primarily during active wake and return the firing rates of individual cells to cell-specific set points.
The most complete single-neuron transcriptome database of the mouse visual cortex was performed using a large collection of reporter mouse lines. Results highlight the unmatched neuronal diversity of the cerebral cortex.
Previous work has suggested that cortical recurrent circuits can self-sustain their activity without thalamic input. A study now demonstrates that this is not the case in the awake brain, which tightly locks cortical timing to thalamic activity.