Standards

Definition

Standards in research refer to a specified level of quality or achievement. For example, in medical research, reporting standards have been drawn up to ensure authors of publications report everything necessary for a full understanding and replication of published research. Standards can also include agreed nomenclature or identifiers.

Latest Research and Reviews

  • Reviews |

    Technical errors can hamper the interpretation of next-generation sequencing (NGS) data, which poses a major challenge for the clinical application of this technology. This Review discusses how reference standards circumvent this issue by calibrating NGS measurements and evaluating diagnostic performance of NGS-based genetic tests.

    • Simon A. Hardwick
    • , Ira W. Deveson
    •  & Tim R. Mercer
  • Research | | open

    The Quest for Orthologs consortium compares the performance of a large number of established orthology inference methods on 20 benchmarks and provides a free web tool for methods developers to facilitate further benchmarking.

    • Adrian M Altenhoff
    • , Brigitte Boeckmann
    • , Salvador Capella-Gutierrez
    • , Daniel A Dalquen
    • , Todd DeLuca
    • , Kristoffer Forslund
    • , Jaime Huerta-Cepas
    • , Benjamin Linard
    • , Cécile Pereira
    • , Leszek P Pryszcz
    • , Fabian Schreiber
    • , Alan Sousa da Silva
    • , Damian Szklarczyk
    • , Clément-Marie Train
    • , Peer Bork
    • , Odile Lecompte
    • , Christian von Mering
    • , Ioannis Xenarios
    • , Kimmen Sjölander
    • , Lars Juhl Jensen
    • , Maria J Martin
    • , Matthieu Muffato
    • , Quest for Orthologs consortium
    • , Adrian M Altenhoff
    • , Brigitte Boeckmann
    • , Salvador Capella-Gutierrez
    • , Todd DeLuca
    • , Kristoffer Forslund
    • , Jaime Huerta-Cepas
    • , Benjamin Linard
    • , Cécile Pereira
    • , Leszek P Pryszcz
    • , Fabian Schreiber
    • , Alan Sousa da Silva
    • , Damian Szklarczyk
    • , Clément-Marie Train
    • , Odile Lecompte
    • , Ioannis Xenarios
    • , Kimmen Sjölander
    • , Maria J Martin
    • , Matthieu Muffato
    • , Toni Gabaldón
    • , Suzanna E Lewis
    • , Paul D Thomas
    • , Erik Sonnhammer
    • , Christophe Dessimoz
    • , Toni Gabaldón
    • , Suzanna E Lewis
    • , Paul D Thomas
    • , Erik Sonnhammer
    •  & Christophe Dessimoz
    Nature Methods 13, 425–430
  • Protocols |

    This protocol summarizes the recommendations developed after a comparison of Elispot plate-reading approaches by a panel of laboratories and subsequent agreement regarding the optimal steps to follow when evaluating Elispot plates.

    • Sylvia Janetzki
    • , Leah Price
    • , Helene Schroeder
    • , Cedrik M Britten
    • , Marij J P Welters
    •  & Axel Hoos
    Nature Protocols 10, 1098–1115

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