Sphingolipids are lipids with a sphingoid base backbone, bearing its own hydrocarbon chain, an amine group and two hydroxyl groups. The amine group is bonded to a fatty acid of varying length and one of the hydroxyl groups may be functionalized to a phosphate or carbohydrate. Sphingolipids are involved in signal transduction across membranes.
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Research Highlights |Nature Chemical Biology 8, 222