Cell reprogramming is the process of reverting mature, specialised cells into induced pluripotent stem cells. Reprogramming also refers to the erasure and re-establishment of epigenetic marks during mammalian germ cell development.

Latest Research and Reviews

News and Comment

  • Research Highlights |

    A new study in Science reports the existence of a subpopulation of somatic cells from which ‘elite’ clones emerge that outperform other clones to drive reprogramming.

    • Linda Koch
  • News and Views |

    An in vivo cellular reprogramming strategy to generate epithelial cells from wound mesenchymal cells promotes healing and provides a new avenue for the treatment of nonhealing wounds.

    • Shruti Naik
    Nature Medicine 24, 1311-1312
  • Research Highlights |

    Kikuë Tachibana discusses some of the key findings of the seminal works of Sir John Gurdon on nuclear reprogramming and how, by being examples of scientific rigour, they have inspired her own research.

    • Kikuë Tachibana
  • News and Views |

    Auxin-induced callus formation, known as a type of cell reprogramming, involves several transcription factors that act in lateral root initiation for plant development. Now, a new partnership of transcription factors is identified to reveal the regulatory network of auxin-induced cell reprogramming.

    • Munetaka Sugiyama
    Nature Plants 4, 69-70