Reproductive signs and symptoms articles from across Nature Portfolio

Hypertension, and organ system dysfunctions associated with preeclampsia (PE) result in poor pregnancy outcomes. In the current study, the authors examined molecular pathogenesis of PE with a focus Peroxisome proliferator-activated receptor gamma (PPARγ), lipid metabolism, and ferroptosis in the placenta of PE patients.

A single-cell RNA sequencing study about POP constructed a transcriptional profile of 30,452 single cells of the uterosacral ligament in human for the first time, revealing a picture of immune cell infiltration in USL tissue of POP samples.

At a time of diminishing clinical skills and diagnostic endeavours for clinicians worldwide, a method of rapid automated microscopy coupled with pH measurement is introduced with early clinical success results in women with common vulvovaginal symptoms facilitating rapid diagnosis and enhanced therapeutic measures.

A cohort study of more than 1,500 births to women with axial spondyloarthritis reveals a trend of improvement in pregnancy outcomes over time.