Regenerative medicine

Regenerative medicine is the branch of medicine that develops methods to regrow, repair or replace damaged or diseased cells, organs or tissues. Regenerative medicine includes the generation and use of therapeutic stem cells, tissue engineering and the production of artificial organs.

Latest Research and Reviews

News and Comment

  • Comments and Opinion |

    Despite initial enthusiasm, poor translation of preclinical studies and high-profile scandals involving stem cell research have hindered the field of regenerative urology in recent years. However, consideration of the potential of regenerative approaches to revolutionize patient care ought to reignite interest and begin a renaissance in regenerative urology research.

    • Margot S. Damaser
    •  & Karl-Dietrich Sievert
  • Comments and Opinion |

    Despite substantial advances, bona fide regeneration of the damaged human heart is still an unmet ambition. By extracting our current knowledge from developmental biology, animal models of heart regeneration, and clinical observations, we propose five hallmarks of cardiac regeneration and suggest a holistic approach to reconstituting human heart function.

    • Alessandro Bertero
    •  & Charles E. Murry
  • Research Highlights |

    A study reports that CRISPR–Cas9 induces extensive on-target mutagenesis in mouse and human cells, calling for greater caution when using it in clinical contexts.

    • Kim Baumann
  • Editorial |

    For cell therapies to transition from promises to products, increased efforts need to be put into the identification of the factors and biological mechanisms that affect safety and efficacy, and into the design of cost-effective methods for the harvesting, expansion, manipulation and purification of the cells.