Featured
-
-
Article
| Open Access
Establishment of a synchronized tyrosinase transport system revealed a role of Tyrp1 in efficient melanogenesis by promoting tyrosinase targeting to melanosomes
- Hikari Nakamura
- & Mitsunori Fukuda
-
Article
| Open Access
Yeast 26S proteasome nuclear import is coupled to nucleus-specific degradation of the karyopherin adaptor protein Sts1
- Carolyn Allain Breckel
- , Zane M. Johnson
- & Mark Hochstrasser
-
Article
| Open Access
In vivo identification of Drosophila rhodopsin interaction partners by biotin proximity labeling
- Nilofar Feizy
- , Sarah Franziska Leuchtenberg
- & Armin Huber
-
Article
| Open Access
Quantitative analysis of peroxisome tracks using a Hidden Markov Model
- Carl-Magnus Svensson
- , Katharina Reglinski
- & Marc Thilo Figge
-
Article
| Open Access
Characterization of signal and transit peptides based on motif composition and taxon-specific patterns
- Katarzyna Sidorczuk
- , Paweł Mackiewicz
- & Przemysław Gagat
-
Article
| Open Access
Site-specific phosphorylations of the Arf activator GBF1 differentially regulate GBF1 function in Golgi homeostasis and secretion versus cytokinesis
- Kendall Walton
- , Tomasz J. Nawara
- & Elizabeth Sztul
-
Article
| Open Access
DARPins bind their cytosolic targets after having been translocated through the protective antigen pore of anthrax toxin
- Lukas Becker
- & Andreas Plückthun
-
Article
| Open Access
Transport of Designed Ankyrin Repeat Proteins through reconstituted human bronchial epithelia and protection against SARS-CoV-2
- Lisa Künzi
- , Sarah Ryter
- & Marianne Geiser
-
Article
| Open Access
Synchronized proinsulin trafficking reveals delayed Golgi export accompanies β-cell secretory dysfunction in rodent models of hyperglycemia
- Cierra K. Boyer
- , Casey J. Bauchle
- & Samuel B. Stephens
-
Article
| Open Access
GLUT2 expression by glial fibrillary acidic protein-positive tanycytes is required for promoting feeding-response to fasting
- M. J. Barahona
- , F. Langlet
- & María A. García-Robles
-
Article
| Open Access
Hydrophobicity is a key determinant in the activity of arginine-rich cell penetrating peptides
- Jason Allen
- & Jean-Philippe Pellois
-
Article
| Open Access
Activation of SIRT1 promotes membrane resealing via cortactin
- Naotoshi Iwahara
- , Kuya Azekami
- & Atsushi Kuno
-
Article
| Open Access
Twin-arginine translocase component TatB performs folding quality control via a chaperone-like activity
- May N. Taw
- , Jason T. Boock
- & Matthew P. DeLisa
-
Article
| Open Access
A systematic exploration reveals the potential of spermidine for hypopigmentation treatment through the stabilization of melanogenesis-associated proteins
- Sofia Brito
- , Hyojin Heo
- & Bum-Ho Bin
-
Article
| Open Access
Selective binding and transport of protocadherin 15 isoforms by stereocilia unconventional myosins in a heterologous expression system
- Angela Ballesteros
- , Manoj Yadav
- & Bechara Kachar
-
Article
| Open Access
The dynamics of protein localisation to restricted zones within Drosophila mechanosensory cilia
- Wangchu Xiang
- , Petra zur Lage
- & Andrew P. Jarman
-
Article
| Open Access
Internalization and trafficking of CSPG-bound recombinant VAR2CSA lectins in cancer cells
- Chris Kedong Wang
- , Irina Nelepcu
- & Mads Daugaard
-
Article
| Open Access
Intracellular translocation of HMGB1 is important for Zika virus replication in Huh7 cells
- Kim-Ling Chin
- , Nurhafiza Zainal
- & Sazaly AbuBakar
-
Article
| Open Access
Structural characterization of human importin alpha 7 in its cargo-free form at 2.5 Å resolution
- S. Tsimbalyuk
- , C. M. Donnelly
- & J. K. Forwood
-
Article
| Open Access
Identification of an epithelial-mesenchymal transition-related lncRNA prognostic signature for patients with glioblastoma
- XinJie Yang
- , Sha Niu
- & XiaoChun Jiang
-
Article
| Open Access
Expression of truncated Kir6.2 promotes insertion of functionally inverted ATP-sensitive K+ channels
- Benjamin A. Heitz
- , Robert Bränström
- & Craig A. Aspinwall
-
Article
| Open Access
Nucleolar translocation of human DNA topoisomerase II by ATP depletion and its disruption by the RNA polymerase I inhibitor BMH-21
- Keiko Morotomi-Yano
- & Ken-ichi Yano
-
Article
| Open Access
Distinct mutations in importin-β family nucleocytoplasmic transport receptors transportin-SR and importin-13 affect specific cargo binding
- Makoto Kimura
- , Kenichiro Imai
- & Naoko Imamoto
-
Article
| Open Access
Identification of cis-acting determinants mediating the unconventional secretion of tau
- Taxiarchis Katsinelos
- , William A. McEwan
- & Walter Nickel
-
Article
| Open Access
Centrosomal P4.1-associated protein (CPAP) positively regulates endocytic vesicular transport and lysosome targeting of EGFR
- Radhika Gudi
- , Viswanathan Palanisamy
- & Chenthamarakshan Vasu
-
Article
| Open Access
ALS-linked FUS mutants affect the localization of U7 snRNP and replication-dependent histone gene expression in human cells
- Ankur Gadgil
- , Agnieszka Walczak
- & Katarzyna Dorota Raczyńska
-
Article
| Open Access
Ipomoeassin-F disrupts multiple aspects of secretory protein biogenesis
- Peristera Roboti
- , Sarah O’Keefe
- & Stephen High
-
Article
| Open Access
A human infertility-associated KASH5 variant promotes mitochondrial localization
- Sana A. Bentebbal
- , Bakhita R. Meqbel
- & Henning F. Horn
-
Article
| Open Access
Clinically-identified C-terminal mutations in fibulin-3 are prone to misfolding and destabilization
- DaNae R. Woodard
- , Emi Nakahara
- & John D. Hulleman
-
Article
| Open Access
Cellular dynamics of the SecA ATPase at the single molecule level
- Anne-Bart Seinen
- , Dian Spakman
- & Arnold J. M. Driessen
-
Article
| Open Access
CCDC66 frameshift variant associated with a new form of early-onset progressive retinal atrophy in Portuguese Water Dogs
- Leonardo Murgiano
- , Doreen Becker
- & Keiko Miyadera
-
Article
| Open Access
Identification of a nuclear localization signal in the Plasmodium falciparum CTP: phosphocholine cytidylyltransferase enzyme
- Richard Izrael
- , Lívia Marton
- & Beáta G. Vértessy
-
Article
| Open Access
Transportin-2 plays a critical role in nucleocytoplasmic shuttling of oestrogen receptor-α
- Tetsuji Moriyama
- , Yoshihiro Yoneda
- & Masami Yamada
-
Article
| Open Access
Cell-penetrating peptide-mediated cell entry of H5N1 highly pathogenic avian influenza virus
- Naoki Kajiwara
- , Namiko Nomura
- & Futoshi Shibasaki
-
Article
| Open Access
Tagging the proteasome active site β5 causes tag specific phenotypes in yeast
- Kenrick A. Waite
- , Alicia Burris
- & Jeroen Roelofs
-
Article
| Open Access
TBC1D1 interacting proteins, VPS13A and VPS13C, regulate GLUT4 homeostasis in C2C12 myotubes
- Sharon C. Hook
- , Alexandra Chadt
- & Elaine C. Thomas
-
Article
| Open Access
Spatial organization of Clostridium difficile S-layer biogenesis
- Peter Oatley
- , Joseph A. Kirk
- & Robert P. Fagan
-
Article
| Open Access
Mouse CD163 deficiency strongly enhances experimental collagen-induced arthritis
- Pia Svendsen
- , Anders Etzerodt
- & Søren K. Moestrup
-
Article
| Open Access
Rescue of mutant gonadotropin-releasing hormone receptor function independent of cognate receptor activity
- Emery Smith
- , Jo Ann Janovick
- & Timothy P. Spicer
-
Article
| Open Access
Role of PKC in the Regulation of the Human Kidney Chloride Channel ClC-Ka
- Andrea Gerbino
- , Roberta De Zio
- & Monica Carmosino
-
Article
| Open Access
Avicin G is a potent sphingomyelinase inhibitor and blocks oncogenic K- and H-Ras signaling
- Christian M. Garrido
- , Karen M. Henkels
- & Kwang-jin Cho
-
Article
| Open Access
Epididymal proteins Binder of SPerm Homologs 1 and 2 (BSPH1/2) are dispensable for male fertility and sperm motility in mice
- Marzieh Eskandari-Shahraki
- , Bruno Prud’homme
- & Puttaswamy Manjunath
-
Article
| Open Access
Development of an experimental method of systematically estimating protein expression limits in HEK293 cells
- Yoshihiro Mori
- , Yuki Yoshida
- & Hisao Moriya
-
Article
| Open Access
Active nuclear import of the deacetylase Sirtuin-2 is controlled by its C-terminus and importins
- Matthew J. G. Eldridge
- , Jorge M. Pereira
- & Mélanie A. Hamon
-
Article
| Open Access
Protein sorting into protein bodies during barley endosperm development is putatively regulated by cytoskeleton members, MVBs and the HvSNF7s
- Valentin Roustan
- , Julia Hilscher
- & Verena Ibl
-
Article
| Open Access
Endomembrane Protein Trafficking Regulated by a TvCyP2 Cyclophilin in the Protozoan Parasite, Trichomonas vaginalis
- Hong-Ming Hsu
- , Yu-Hsin Huang
- & Jung-Hsiang Tai
-
Article
| Open Access
Type 2 diabetes-associated single nucleotide polymorphism in Sorcs1 gene results in alternative processing of the Sorcs1 protein in INS1 β-cells
- Belinda Yau
- , Zachary Blood
- & Melkam A. Kebede
-
Article
| Open Access
Particle Mobility Analysis Using Deep Learning and the Moment Scaling Spectrum
- Marloes Arts
- , Ihor Smal
- & Erik Meijering
-
Article
| Open Access
Contribution of syndecans to cellular uptake and fibrillation of α-synuclein and tau
- Anett Hudák
- , Erzsébet Kusz
- & Tamás Letoha
Apolipoprotein L1 (APOL1) renal risk variant-mediated podocyte cytotoxicity depends on African haplotype and surface expression