Physical sciences

Physical sciences are those academic disciplines that aim to uncover the underlying laws of nature - often written in the language of mathematics. It is a collective term for areas of study including astronomy, chemistry, materials science and physics.

Featured

Latest Research and Reviews

  • Research
    | Open Access

    Prior to anaphase, securin binds separase and thereby prevents cohesin cleavage. Here, the authors develop a method to produce active securin-free separase, identify a docking motif in cohesin that promotes cleavage, and show that securin interferes with this interaction.

    • Laura E. Rosen
    • , Joseph E. Klebba
    • , Jonathan B. Asfaha
    • , Chloe M. Ghent
    • , Melody G. Campbell
    • , Yifan Cheng
    •  & David O. Morgan
  • Research
    | Open Access

    Designing efficient, scalable and low-thermal-budget 2D Materials for 3D integration remains a challenge. Here, the authors report the development of a hybrid-(solution-processed-exfoliated) integration of 2D Material based 1T1R which uses a multilayer WSe2 p-FET and a multilayer printed WSe2 RRAM.

    • Maheswari Sivan
    • , Yida Li
    • , Hasita Veluri
    • , Yunshan Zhao
    • , Baoshan Tang
    • , Xinghua Wang
    • , Evgeny Zamburg
    • , Jin Feng Leong
    • , Jessie Xuhua Niu
    • , Umesh Chand
    •  & Aaron Voon-Yew Thean
  • Reviews |

    Enzyme designers can exploit catalytic promiscuity to unlock activities unknown to nature. This Review discusses how repurposing versatile reaction intermediates and creating new ones installs abiological activities into existing, designed and hybrid enzymes, and how directed-evolution strategies readily improve catalysts for these new-to-nature activities.

    • Reuben B. Leveson-Gower
    • , Clemens Mayer
    •  & Gerard Roelfes
  • Research
    | Open Access

    While dry reforming of methane, the reaction of CH4 and CO2 to create CO and H2, is a promising reaction for industry, coke buildup often deactivates catalysts and limits commercialization. Here, authors report single-atom nickel on Ce-doped hydroxyapatite as a coke-resistant catalyst.

    • Mohcin Akri
    • , Shu Zhao
    • , Xiaoyu Li
    • , Ketao Zang
    • , Adam F. Lee
    • , Mark A. Isaacs
    • , Wei Xi
    • , Yuvaraj Gangarajula
    • , Jun Luo
    • , Yujing Ren
    • , Yi-Tao Cui
    • , Lei Li
    • , Yang Su
    • , Xiaoli Pan
    • , Wu Wen
    • , Yang Pan
    • , Karen Wilson
    • , Lin Li
    • , Botao Qiao
    • , Hirofumi Ishii
    • , Yen-Fa Liao
    • , Aiqin Wang
    • , Xiaodong Wang
    •  & Tao Zhang
  • Research
    | Open Access

    Imaging heart development is challenging due to constant tissue movement and changing physical landmarks. Here the authors present an algorithm capable of maintaining phase-locked imaging throughout a 24 hour timespan, enabling long term timelapse imaging studies of zebrafish heart development, repair and regeneration.

    • Jonathan M. Taylor
    • , Carl J. Nelson
    • , Finnius A. Bruton
    • , Aryan K. Baghbadrani
    • , Charlotte Buckley
    • , Carl S. Tucker
    • , Adriano G. Rossi
    • , John J. Mullins
    •  & Martin A. Denvir

News and Comment

  • News and Views |

    A study in Nature Metabolism reveals a hitherto-unknown enzymatic and physiological role of ABHD5, which acts as a protease that couples extracellular cues to the epigenome of cardiomyocytes by cleaving histone deacetylase 4 (HDAC4).

    • Joshua G. Travers
    •  & Timothy A. McKinsey
    Nature Metabolism 1, 1034-1035
  • Editorial |

    Plastic waste is a serious matter of concern due to its disruptive impact on the environment. While disposal and reclaim strategies represent the first lines of intervention to solve this problem, upcycling options based on catalytic transformations will eventually be necessary to reconvert enormous quantities of such material.

    Nature Catalysis 2, 945-946
  • Research Highlights |

    Biological tissues are scaffolded by the extracellular matrix, but details of how this network of fibre-like macromolecules is patterned have remained elusive. Two papers demonstrate the role of feedback between cells and matrix, and identify how the mechanism is regulated.

    • Zoe Budrikis
  • Editorial |

    The revolutionary work of John Goodenough, M. Stanley Whittingham and Akira Yoshino has finally been awarded the Nobel Prize in Chemistry. Scientific discovery and engineering brilliance continue to shape battery technology.

    Nature Energy 4, 893