Phylogenomics involves the reconstruction of evolutionary relationships by comparing sequences of whole genomes or portions of genomes.

Latest Research and Reviews

News and Comment

  • Editorial |

    Whereas once it was only possible to generate reference genome sequences one at a time, it is now feasible to design genomic experiments to maximize functional comparisons and contrasts among many genomes. Investigating the diversity of a number of related parasite genomes and their transcriptomes in multiple contexts increasingly shows us ways to intervene in the ecological and evolutionary strategies of pathogens.

  • News and Views |

    Shigella sonnei is an important cause of bacterial dysentery in the developed world and has also recently emerged in transitional countries. Phylogenetic analysis based on whole-genome sequencing of a global sample has detailed the recent evolutionary history of this pathogen and shed light on the genetic changes associated with this epidemiological shift.

    • Edward J Feil
    Nature Genetics 44, 964–965