Phase III trials
Phase III trials are conducted to provide stronger evidence of the effectiveness and safety of a therapeutic intervention and typically form a key part of applications to regulatory authorities to grant market approval. They usually involve 500-3000 or more patients and compare the therapeutic intervention with the current standard of care for patients with the disease intended to be treated.
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Long-term findings from COMFORT-II, a phase 3 study of ruxolitinib vs best available therapy for myelofibrosisLeukemia 30, 1701–1707
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Research Highlights |Nature Reviews Clinical Oncology 14, 586