Uptake of apoptotic cell corpses by phagocytes requires the coordinated activity of SLC family membrane transporters to meet the metabolic demands of anti-inflammatory dead cell clearance.

Activation of aryl hydrocarbon receptor in phago cytes during apoptotic cell uptake induces an anti-inflammatory response.

Free heme released by hemolysis directly inhibits bacterial phagocytosis by macrophages via alterations of actin cytoskeletal dynamics.

Macrophages regulate phagocytic and inflammatory responses by non-professional phagocytes.

Perivascular and subdural meningeal macrophages at the interface between the central nervous system and the periphery are self-renewing and arise from early embryonic precursors. Macrophages residing in the choroid plexus have dual origin, developing from circulating bone-marrow-derived monocytes and embryonic progenitors.