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The peripheral nervous system is the part of the nervous system outside the brain and spinal cord. It consists of nerves that carry information between the central nervous system and the extremities of the body.
Sympathetic nerves associate with tumours and regulate the tumour microenvironment. How this innervation promotes tumorigenesis is unclear. A new study in Science shows that β-adrenergic signalling controls tumour growth by promoting tumour angiogenesis, through the regulation of vascular metabolism.
A Cre-dependent capsid selection method, CREATE, was used to produce adeno-associated viral vectors that allow gene delivery to the entire central and peripheral nervous systems, with multicolor labeling of single cells.