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Pain management refers to a therapy that is directed at ameliorating pain and suffering and improving health-related quality of life in patients with pain. It includes analgaesic, anxiolytic and non-pharmacological treatments.
Neuropathic pain is caused by a lesion or disease of the somatosensory system (including peripheral and central neurons). Here, the authors present the current descriptions of the presentation, causes, diagnosis and treatment of neuropathic pain with a focus on peripheral neuropathic pain, which has a greater knowledge base than central neuropathic pain.
A retrospective population-based cohort study has shown that outcomes were worse for patients with neuropathic pain who received long-term opioid treatment than for those who received short-term opioid treatment. The finding highlights a need for improved pain education for non-specialists and for more-effective therapies.
Pain in osteoarthritis (OA) can be resistant to the medical and surgical treatments currently in use. Local denervation of the arthritic joint could offer a new approach to relieve OA pain, if the results of a new cryoneurolysis clinical trial are confirmed.
Inhibitors of β-nerve growth factor (NGF) have impressive effects in reducing musculoskeletal pain, but have also been associated with adverse events of unclear aetiology. Several studies in the past year have sought to clarify the relative benefits and risks of anti-NGF treatment.