Musculoskeletal models articles from across Nature Portfolio

Criteria for evaluating joint articulation in vertebrates are lacking. Here, the authors propose an approach for combining measurements of 3D articular overlap, symmetry, and congruence into a single metric, and apply this to examine the walking stride of Deinonychus antirrhopus.

Widespread editing of the mutated DMD gene by CRISPR–Cas9, systemically delivered via an adeno-associated virus, restores dystrophin expression in a canine model of Duchenne muscular dystrophy.

Engineered skeletal muscle self-repairs when incorporating bone-marrow-derived macrophages, which prevent the apoptosis of resident muscle stem cells.