Multivesicular bodies (MVBs) are a specialised subset of endosomes that contain membrane-bound intraluminal vesicles. These vesicles form by budding into the lumen of the MVB. The content of MVBs can be degraded, via fusion with lysosomes, or released into the extracellular space, via fusion with the plasma membrane.
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Research Highlights |Nature Reviews Molecular Cell Biology 15, 150–151