Motility disorders

Definition

Motility disorders are characterized by abnormal movements of the gastrointestinal tract, causing the abnormal transit – slow or fast – of contents in the absence of mucosal disease or obstruction. Motility disorders can affect any part of the gastrointestinal tract. Examples of motility disorders include achalasia, gastroparesis, intestinal pseudo-obstruction and faecal incontinence.

Latest Research and Reviews

  • Reviews |

    Rotaviruses are double-stranded RNA viruses that are a leading cause of severe, dehydrating gastroenteritis in children <5 years of age. This Primer gives an overview of the pathophysiology of rotavirus infection and describes how the introduction of vaccinations has altered the epidemiology and demographics of this disease.

    • Sue E. Crawford
    • , Sasirekha Ramani
    • , Jacqueline E. Tate
    • , Umesh D. Parashar
    • , Lennart Svensson
    • , Marie Hagbom
    • , Manuel A. Franco
    • , Harry B. Greenberg
    • , Miguel O'Ryan
    • , Gagandeep Kang
    • , Ulrich Desselberger
    •  & Mary K. Estes
  • Reviews |

    Functional dyspepsia is a functional gastrointestinal disorder characterized by discomfort or pain in the upper abdomen (generally associated with food intake) with no apparent underlying organic cause. The three subtypes of functional dyspepsia are postprandial distress syndrome, epigastric pain syndrome and a subtype with mixed features.

    • Paul Enck
    • , Fernando Azpiroz
    • , Guy Boeckxstaens
    • , Sigrid Elsenbruch
    • , Christine Feinle-Bisset
    • , Gerald Holtmann
    • , Jeffrey M. Lackner
    • , Jukka Ronkainen
    • , Michael Schemann
    • , Andreas Stengel
    • , Jan Tack
    • , Stephan Zipfel
    •  & Nicholas J. Talley
  • Research | | open

    • Carolin Wohlfarth
    • , Stefanie Schmitteckert
    • , Janina D. Härtle
    • , Lesley A. Houghton
    • , Harsh Dweep
    • , Marina Fortea
    • , Ghazaleh Assadi
    • , Alexander Braun
    • , Tanja Mederer
    • , Sarina Pöhner
    • , Philip P. Becker
    • , Christine Fischer
    • , Martin Granzow
    • , Hubert Mönnikes
    • , Emeran A. Mayer
    • , Gregory Sayuk
    • , Guy Boeckxstaens
    • , Mira M. Wouters
    • , Magnus Simrén
    • , Greger Lindberg
    • , Bodil Ohlsson
    • , Peter Thelin Schmidt
    • , Aldona Dlugosz
    • , Lars Agreus
    • , Anna Andreasson
    • , Mauro D’Amato
    • , Barbara Burwinkel
    • , Justo Lorenzo Bermejo
    • , Ralph Röth
    • , Felix Lasitschka
    • , Maria Vicario
    • , Marco Metzger
    • , Javier Santos
    • , Gudrun A. Rappold
    • , Cristina Martinez
    •  & Beate Niesler
  • Reviews | | open

    High-resolution manometry (HRM) has transformed our understanding of oesophageal motility disorders, in particular achalasia. In this Consensus Statement, the authors explore the effect HRM has had on the diagnosis and management of achalasia and related syndromes.

    • Peter J. Kahrilas
    • , Albert J. Bredenoord
    • , Mark Fox
    • , C. Prakash Gyawali
    • , Sabine Roman
    • , André J.P.M. Smout
    • , John E. Pandolfino
    •  & on behalf of the International Working Group for Disorders of Gastrointestinal Motility and Function
  • Reviews | | open

    The diagnosis of GERD using functional oesophageal testing has been previously reported, but no updated expert recommendations have been made in over a decade. In this Consensus Statement, the authors describe modern oesophageal physiological tests and their analysis with an emphasis on establishing indications and interpretation parameters for evaluating GERD in clinical practice.

    • Edoardo Savarino
    • , Albert J. Bredenoord
    • , Mark Fox
    • , John E. Pandolfino
    • , Sabine Roman
    • , C. Prakash Gyawali
    •  & on behalf of the International Working Group for Disorders of Gastrointestinal Motility and Function

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