Monokines

Monokines are cytokines produced mainly by monocytes and macrophages for function in the immune system. Monokines can function as chemoattractants for guiding neutrophil migration.

Latest Research and Reviews

  • Research | | open

    Spondyloarthritis is an inflammatory disease with Th17 cells implicated in the pathogenesis. Here the authors show that patients with spondyloarthritis have increased numbers of GM-CSF-secreting blood and synovial lymphocytes, Th17 or not, that carry a unique transcriptional profile including enhanced GPR65 expression.

    • M. H. Al-Mossawi
    • , L. Chen
    • , H. Fang
    • , A. Ridley
    • , J. de Wit
    • , N. Yager
    • , A. Hammitzsch
    • , I. Pulyakhina
    • , B. P. Fairfax
    • , D. Simone
    • , Yao Yi
    • , S. Bandyopadhyay
    • , K. Doig
    • , R Gundle
    • , B. Kendrick
    • , F. Powrie
    • , J. C. Knight
    •  & P. Bowness