Long-term memory


Long-term memory is information encoded in the brain on the time-scale of years. It consists of explicit (declarative) memories that are consciously reportable and depend heavily on the medial temporal lobe and hippocampus and implicit (procedural) memories that are unconscious and depend on the basal ganglia and cerebellum.

Latest Research and Reviews

News and Comment

  • Research Highlights |

    A new study in mice shows that memory engram cells associated with long-term memories form in the prefrontal cortex early during learning in a contextual fear conditioning paradigm and reveals details of the circuitry involved in long-term memory consolidation.

    • Darran Yates
  • Comments and Opinion |

    Recent human neuroimaging studies suggest that, in addition to its role in visuospatial and sensorimotor processes, the posterior parietal cortex (PPC) also plays an important part in episodic memory retrieval. Here, Sestieri, Shulman and Corbetta present a functional–anatomical model of the involvement of the PPC in memory retrieval.

    • Carlo Sestieri
    • , Gordon L. Shulman
    •  & Maurizio Corbetta
  • News and Views |

    Evidence reveals that humans share remarkably similar patterns of event-specific neural activity during spontaneous spoken recall. Posterior medial cortex appears to play a key role in transforming experience into memory.

    • Eva Zita Patai
    •  & Hugo J Spiers
  • News and Views |

    The inability of adults to retrieve episodic memories of infancy is referred to as infantile amnesia. A study now provides one of the first explanations of the neurobiological mechanisms underlying this phenomenon.

    • Andrii Rudenko
    •  & Li-Huei Tsai
    Nature Neuroscience 19, 1190–1191