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The insula, or insular cortex, is a part of the cerebral cortex located at the base of the Sylvian fissure, and is involved in the processing of emotions, memory, taste, and regulation of the autonomic nervous system.
Recent work suggests that the insula forms part of a network that mediates the processing of salient stimuli. In this Opinion article, Lucina Q. Uddin examines the role of the insula in salience processing before outlining that dysfunction of such processing in insular subdivisions might accompany several brain disorders.