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The effective detection of Helicobacter pylori has been a challenge clinically. Here, the authors demonstrate the potential of magnetic nanoparticles for non-invasive diagnosis of H. pylori using magnetic resonance imaging in vivo.
Liquid metals are excellent candidate materials for biomedicine, owing to their
intriguing optical properties and chemical stability. Here, the authors design
multifunctional theranostic liquid metal nanocapsules that, upon irradiation, generate
heat and reactive oxygen species and change shape to release drugs.
The signal detected in magnetic resonance imaging comes from the relaxation of proton nuclear magnetization. Here, Zhou et al. introduce magnetic field inhomogeneity as a parameter to design iron oxide nanoparticle clusters to enhance the relaxation rate of nearby protons, thereby increasing image contrast.