Idiopathic inflammatory myopathies

The idiopathic inflammatory myopathies are a heterogeneous group of connective tissue diseases of unknown aetiology characterized by chronic inflammation of skeletal muscle, or myositis. The main types of idiopathic inflammatory myopathies are polymyositis, dermatomyositis and inclusion-body myositis.

Latest Research and Reviews

  • Reviews |

    Multiple genetic and environmental factors contribute to the risk of developing idiopathic inflammatory myopathies; both immune and non-immune related mechanisms are involved in the pathogenesis of these disorders, the understanding of which might lead to novel treatment approaches.

    • Frederick W. Miller
    • , Janine A. Lamb
    • , Jens Schmidt
    •  & Kanneboyina Nagaraju
  • Reviews |

    Myositis-specific or myositis-associated antibodies can be found in most patients with myositis and are associated with distinct disease phenotypes. These antibodies also provide valuable insights into the pathogenesis of myositis and can help guide treatment.

    • Neil J. McHugh
    •  & Sarah L. Tansley
  • Reviews |

    The idiopathic inflammatory myopathies are a group of disorders that involve inflammation of skeletal muscles and extramuscular manifestations. New classification criteria capture a broad range of these disorders but should be further defined in the future to incorporate new data.

    • Ingrid E. Lundberg
    • , Marianne de Visser
    •  & Victoria P. Werth
  • Reviews |

    The idiopathic inflammatory myopathies are characterized by muscle weakness and inflammation. A range of tools are available to evaluate outcomes in the treatment of myositis, including, among others, core set measures that were developed by international networks of myositis researchers.

    • Lisa G. Rider
    • , Rohit Aggarwal
    • , Pedro M. Machado
    • , Jean-Yves Hogrel
    • , Ann M. Reed
    • , Lisa Christopher-Stine
    •  & Nicolino Ruperto

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