Hypocretin

Hypocretin (also known as orexin) is a neuropeptide hormone produced in the hypothalamus that exerts important influences over sleep, arousal, appetite and energy expenditure. Defective hypocretin signalling is associated with narcolepsy.

Latest Research and Reviews

News and Comment

  • Research Highlights |

    The brains of individuals who have been addicted to opiate drugs show an increase in the number of hypocretin-expressing neurons — the same neurons that are lost in individuals with narcolepsy.

    • Natasha Bray