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Humoral immunity refers to antibody-mediated immune responses. Antibodies are produced by plasma cells and protect the host from infection in three main ways: by binding to pathogens to inhibit their toxic effects or infectivity (neutralization), by coating pathogens and facilitating their uptake and killing by phagocytes (opsonization) and by activating the complement cascade.
- Nature Immunology 18, 1185–1186
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