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The Golgi is a cytoplasmic organelle composed of stacks of flat membrane-bound structures called cisternae. Within the Golgi, proteins are modified, sorted and packaged for transport to other cellular destinations.
VPS15 is known as a VPS34-associated protein that functions in intracellular trafficking and autophagy. Here the authors identify a role for VPS15 in ciliopathy and ciliary phenotypes, and show that it interacts with GM130 and functions in IFT20-dependent cis-Golgi to cilium trafficking.