Genomics

Genomics is the study of the full genetic complement of an organism (the genome). It employs recombinant DNA, DNA sequencing methods, and bioinformatics to sequence, assemble, and analyse the structure and function of genomes.

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News and Comment

  • News and Views |

    Three recent metagenomic studies analyse methanogenesis-related genes in previously uncharacterized, sediment-inhabiting archaeal lineages. They elucidate the metabolic capacity encoded in the genomes of these lineages, yet how these organisms harness energy is still a mystery.

    • Joana C. Xavier
    •  & William F. Martin
    Nature Microbiology 4, 547-549
  • News and Views |

    Rapid diagnostic tests capable of detecting any potential pathogen are needed to improve the efficacy of antimicrobial therapy and inform antimicrobial stewardship efforts. A new metagenomics-based test that detects microbial DNA in human blood can identify a diverse array of pathogens from any source in the body.

    • Justin O’Grady
    Nature Microbiology 4, 554-555
  • Comments and Opinion |

    We discussed with five scientists what the sources and roles of real-world evidence are, how we can use such data in clinical trials and how these data can be converted into useful information that can impact patient management and regulatory decisions in oncology.

    • Hannah Stower