Genetic databases

A genetic database is one or more sets of genetic data (genes, gene products, variants, phenotypes) stored together with software to enable users to retrieve genetic data, add genetic data and extract information from the data. Genetic databases are repositories of organised data that are a resource for understanding how organisms function.

Latest Research and Reviews

  • Research |

    • Kazuki Takeda
    • , Ikuyo Kou
    • , Nao Otomo
    • , Anna Grauers
    • , Yan-Hui Fan
    • , Yoji Ogura
    • , Yohei Takahashi
    • , Yukihide Momozawa
    • , Elisabet Einarsdottir
    • , Juha Kere
    • , Noriaki Kawakami
    • , Taichi Tsuji
    • , Koki Uno
    • , Teppei Suzuki
    • , Manabu Ito
    • , Shohei Minami
    • , Toshiaki Kotani
    • , Tsuyoshi Sakuma
    • , Haruhisa Yanagida
    • , Hiroshi Taneichi
    • , Ikuho Yonezawa
    • , Hideki Sudo
    • , Kazuhiro Chiba
    • , Naobumi Hosogane
    • , Kotaro Nishida
    • , Kenichiro Kakutani
    • , Tsutomu Akazawa
    • , Takashi Kaito
    • , Kei Watanabe
    • , Katsumi Harimaya
    • , Yuki Taniguchi
    • , Hideki Shigematsu
    • , Satoru Demura
    • , Takahiro Iida
    • , Katsuki Kono
    • , Eijiro Okada
    • , Nobuyuki Fujita
    • , Mitsuru Yagi
    • , Morio Matsumoto
    • , Yong Qiu
    • , You-Qiang Song
    • , Paul Gerdhem
    • , Kota Watanabe
    •  & Shiro Ikegawa
  • Research |

    Assessment of metagenomic sequencing of cell-free DNA directly from patient samples as a diagnostic for infections.

    • Timothy A. Blauwkamp
    • , Simone Thair
    • , Michael J. Rosen
    • , Lily Blair
    • , Martin S. Lindner
    • , Igor D. Vilfan
    • , Trupti Kawli
    • , Fred C. Christians
    • , Shivkumar Venkatasubrahmanyam
    • , Gregory D. Wall
    • , Anita Cheung
    • , Zoë N. Rogers
    • , Galit Meshulam-Simon
    • , Liza Huijse
    • , Sanjeev Balakrishnan
    • , James V. Quinn
    • , Desiree Hollemon
    • , David K. Hong
    • , Marla Lay Vaughn
    • , Mickey Kertesz
    • , Sivan Bercovici
    • , Judith C. Wilber
    •  & Samuel Yang
  • Research | | open

    Genetic variants might exert their functional effects via influencing molecular interaction. Here, the authors present a resource featuring almost 28,000 annotations describing the effect of small sequence changes on physical protein interactions, curated by IMEx Consortium curators.

    • N. del-Toro
    • , M. Duesbury
    • , M. Koch
    • , L. Perfetto
    • , A. Shrivastava
    • , D. Ochoa
    • , O. Wagih
    • , J. Piñero
    • , M. Kotlyar
    • , C. Pastrello
    • , P. Beltrao
    • , L. I. Furlong
    • , I. Jurisica
    • , H. Hermjakob
    • , S. Orchard
    • , P. Porras
    • , J. Khadake
    • , B. Meldal
    • , S. Panni
    • , D. Thorneycroft
    • , K. van Roey
    • , S. Abbani
    • , L. Salwinski
    • , M. Pellegrini
    • , M. Iannuccelli
    • , L. Licata
    • , G. Cesareni
    • , B. Roechert
    • , A. Bridge
    • , M. G. Ammari
    • , F. McCarthy
    • , F. Broackes-Carter
    • , N. H. Campbell
    • , A. N. Melidoni
    • , M. Rodriguez-Lopez
    • , R. C. Lovering
    • , S. Jagannathan
    • , C. Chen
    • , D. J. Lynn
    • , S. Ricard-Blum
    • , U. Mahadevan
    •  & A. Raghunath
  • Research | | open

    This paper presents standards and best practices for reporting genome sequences of uncultivated viruses.

    • Simon Roux
    • , Evelien M Adriaenssens
    • , Bas E Dutilh
    • , Eugene V Koonin
    • , Andrew M Kropinski
    • , Mart Krupovic
    • , Jens H Kuhn
    • , Rob Lavigne
    • , J Rodney Brister
    • , Arvind Varsani
    • , Clara Amid
    • , Ramy K Aziz
    • , Seth R Bordenstein
    • , Peer Bork
    • , Mya Breitbart
    • , Guy R Cochrane
    • , Rebecca A Daly
    • , Christelle Desnues
    • , Melissa B Duhaime
    • , Joanne B Emerson
    • , François Enault
    • , Jed A Fuhrman
    • , Pascal Hingamp
    • , Philip Hugenholtz
    • , Bonnie L Hurwitz
    • , Natalia N Ivanova
    • , Jessica M Labonté
    • , Kyung-Bum Lee
    • , Rex R Malmstrom
    • , Manuel Martinez-Garcia
    • , Ilene Karsch Mizrachi
    • , Hiroyuki Ogata
    • , David Páez-Espino
    • , Marie-Agnès Petit
    • , Catherine Putonti
    • , Thomas Rattei
    • , Alejandro Reyes
    • , Francisco Rodriguez-Valera
    • , Karyna Rosario
    • , Lynn Schriml
    • , Frederik Schulz
    • , Grieg F Steward
    • , Matthew B Sullivan
    • , Shinichi Sunagawa
    • , Curtis A Suttle
    • , Ben Temperton
    • , Susannah G Tringe
    • , Rebecca Vega Thurber
    • , Nicole S Webster
    • , Katrine L Whiteson
    • , Steven W Wilhelm
    • , K Eric Wommack
    • , Tanja Woyke
    • , Kelly C Wrighton
    • , Pelin Yilmaz
    • , Takashi Yoshida
    • , Mark J Young
    • , Natalya Yutin
    • , Lisa Zeigler Allen
    • , Nikos C Kyrpides
    •  & Emiley A Eloe-Fadrosh
  • Research | | open

    Short-tandem repeats (STR), similar to single nucleotide polymorphisms (SNP), contribute to complex traits, but their ascertainment by next-generation sequencing is costly. Here, Saini et al. provide a SNP+STR haplotype reference panel that allows imputation of STRs from SNP array data.

    • Shubham Saini
    • , Ileena Mitra
    • , Nima Mousavi
    • , Stephanie Feupe Fotsing
    •  & Melissa Gymrek

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