Fungal genomics articles from across Nature Portfolio

Coccidioidomycosis, a WHO-listed mycosis, is neglected in South America. Analysis of 292 cases in Brazil, often tied to armadillo hunting, unveils unique disease patterns, environmental factors and pathogen genetics causing the disease.

Whole-genome analysis of 876 Aspergillus fumigatus strains including 171 strains from Japan highlights the diversity in the A. fumigatus strains isolated in Japan as well as the complexity in the global distribution of the pathogenic strains.

The spatial organization of eukaryotic genomes is linked to their biological functions. Here, the authors study the 3D genome organization of the phytopathogenic fungus Verticillium dahliae, revealing links to evolutionary features conserved throughout the Verticillium genus.

Candida tropicalis is a cause of invasive candidiasis infection in humans that has been increasingly associated with azole drug resistance. In this study, the authors investigate the genetic basis for azole resistance through analysis of whole-genome sequencing and multilocus sequence typing data.

This study shows that healthy individuals are reservoirs for genotypically and phenotypically diverse Candida albicans strains that retain their capacity to cause disease.

This month’s Genome Watch highlights the genomic traits underlying the ancestral association between endobacteria, which live inside arbuscular mycorrhizal fungi, which reside within plants.

This study reports that extensive copy number variations occur in the presence of azole antifungal drugs in Candida albicans, which might cause phenotypic and population-level heterogeneity observed in clinical isolates.

This study reports the discovery of human-pathogenic filamentous Aspergillus latus allodiploid hybrids that are phenotypically distinct from the parental species.

This month’s Genome Watch highlights a large-scale sequencing project that enriches our understanding of yeast evolution and diversity.