Functional magnetic resonance imaging

Definition

Functional magnetic resonance imaging is a non-invasive method for measuring brain activity. It uses magnetic resonance imaging to map blood oxygenation levels in the brain and estimate changes in blood flow that are correlated with brain activity.

Latest Research and Reviews

News and Comment

  • Comments and Opinion |

    Transcranial magnetic stimulation (TMS) is emerging as a potential broad-spectrum therapy for addiction. In this Opinion article, Diana and colleagues discuss the neural foundations of TMS and discuss possible mechanisms underlying the beneficial effects observed in people with addictions.

    • Marco Diana
    • , Tommi Raij
    • , Miriam Melis
    • , Aapo Nummenmaa
    • , Lorenzo Leggio
    •  & Antonello Bonci
  • Comments and Opinion |

    Recent human neuroimaging studies suggest that, in addition to its role in visuospatial and sensorimotor processes, the posterior parietal cortex (PPC) also plays an important part in episodic memory retrieval. Here, Sestieri, Shulman and Corbetta present a functional–anatomical model of the involvement of the PPC in memory retrieval.

    • Carlo Sestieri
    • , Gordon L. Shulman
    •  & Maurizio Corbetta
  • News and Views |

    A new study identifies four distinct 'biotypes' of depression on the basis of fMRI resting-state functional connectivity in a diverse sample of more than 1,000 individuals. The biotypes are diagnostic of depression and predict treatment response.

    • Tor D Wager
    •  & Choong-Wan Woo
    Nature Medicine 23, 16–17
  • Comments and Opinion |

    The anatomical complexity and location of the human subcortex render it difficult to study by MRI in vivo. Here, Forstmann et al. argue that understanding subcortex function may be facilitated by combining in vivo and post-mortem ultra-high field MRI, post-mortem histology and modelling approaches.

    • Birte U. Forstmann
    • , Gilles de Hollander
    • , Leendert van Maanen
    • , Anneke Alkemade
    •  & Max C. Keuken
  • News and Views |

    During synaptic activation, the function of astrocyte endfeet depends on the vascular target: at the capillary, but not at the arteriole, a newly described P2X1R–phospholipase D2 pathway modulates prostaglandin E2 release and vessel dilation.

    • Ravi L Rungta
    •  & Serge Charpak
    Nature Neuroscience 19, 1539–1541