Fragile sites are chromosomal regions that are susceptible to gaps or breaks. Common fragile sites occur in all individuals, are thought to be sensitive to replication stress due to chromosome structure, and are often re-arranged in cancer. Rare fragile sites are caused by nucleotide repeats and are inherited.
Latest Research and Reviews
Research | | openNature Communications 8, 15025
Research |Nature 528, 286–290
Research |Nature Communications 6, 7094
News and Comment
Research Highlights |Nature Reviews Molecular Cell Biology 15, 430–431
Research Highlights |Nature Reviews Cancer 14, 450–451