Escherichia coli articles from across Nature Portfolio

Escherichia coli is a rod-shaped Gram-negative bacterium that inhabits the gut of warm-blooded animals. It is a prokaryotic model organism and is widely used as an experimental workhorse for DNA manipulation and protein production. Some strains can be pathogenic to humans.

Latest Research and Reviews

Fluorescent reporters give new insights into antibiotics-induced nonsense and frameshift mistranslation
- Mariliis Hinnu
- Marta Putrinš
- Tanel Tenson
ResearchOpen Access22 Mar 2024 Scientific Reports
Volume: 14, P: 6883
Proteome-wide landscape of solubility limits in a bacterial cell
- Ádám Györkei
- Lejla Daruka
- Balázs Papp
ResearchOpen Access21 Apr 2022 Scientific Reports
Volume: 12, P: 6547
Single-molecule live-cell imaging visualizes parallel pathways of prokaryotic nucleotide excision repair

In Escherichia coli, the UvrAB damage sensor recognizes helix-distorting lesions by itself or via Mfd bound to stalled RNA polymerase. Here authors use single-molecule fluorescence imaging to quantify the kinetic signatures of interactions of UvrA with Mfd and UvrB in live cells.
- Harshad Ghodke
- Han Ngoc Ho
- Antoine M. van Oijen
ResearchOpen Access20 Mar 2020 Nature Communications
Volume: 11, P: 1477
Manipulating rod-shaped bacteria with optical tweezers
- Zheng Zhang
- Tom E. P. Kimkes
- Matthias Heinemann
ResearchOpen Access13 Dec 2019 Scientific Reports
Volume: 9, P: 19086
High yield bacterial expression, purification and characterisation of bioactive Human Tousled-like Kinase 1B involved in cancer
- Siddhant Bhoir
- Althaf Shaik
- Sivapriya Kirubakaran
ResearchOpen Access19 Mar 2018 Scientific Reports
Volume: 8, P: 4796
Long-term growth data of Escherichia coli at a single-cell level
- Yu Tanouchi
- Anand Pai
- Lingchong You
ResearchOpen Access28 Mar 2017 Scientific Data
Volume: 4, P: 170036

All Research & Reviews

News and Comment

Modeling the E. coli cell

An integrative modeling framework enables cross-validation of existing E. coli datasets and prediction of uncharacterized parameters.
- Lei Tang
Research Highlights29 Sept 2020 Nature Methods
Volume: 17, P: 958
Gas vesicles enable ultrasound imaging

Acoustic reporter genes that produce gas vesicles offer a way to image and locate microorganisms in mammalian hosts.
- Christian Schnell
Research Highlights28 Feb 2018 Nature Methods
Volume: 15, P: 159
Preparing Rubisco for a tune up

New capabilities for assembling plant Rubisco in bacteria offer a revolution for enhancing photosynthesis. The technology provides a breakthrough to identify and test solutions for improving CO₂ fixation by crop Rubisco.
- Brendon Conlan
- Spencer Whitney
News & Views20 Dec 2017 Nature Plants
Volume: 4, P: 12-13
Hacking rules for E. coli
- Irene Jarchum
News & Views07 Dec 2016 Nature Biotechnology
Volume: 34, P: 1249
Know when to fold 'em
- Grant Miura
Research Highlights15 Nov 2016 Nature Chemical Biology
Volume: 12, P: 989
Counting proteins by slowing diffusion

Research Highlights29 Jun 2016 Nature Methods
Volume: 13, P: 547