Microendoscopy articles from across Nature Portfolio

Fiber-based micro-endoscopes are minimally invasive, but 3D imaging is limited by the need for bulky optical elements or rigid fibers. Here, the authors demonstrate holographic imaging through flexible and dynamically bent multi-core fibers by adding partially reflecting mirror to the distal fiber-tip.

High resolution intravascular imaging in the brain is limited by the high tortuosity of the vasculature. Here the authors present a fiber optic imaging technology using high-frequency optical coherence tomography (HF-OCT) to provide volumetric high resolution images in the highly tortuous cerebral vasculature.

Several key papers published in 2015 highlight important emerging trends in endoscopic imaging that promise to improve patient diagnosis and guidance of therapy. These studies reflect the future role for 'smart' contrast agents and fluorescence endoscopes to provide a molecular basis for disease detection, identify precancerous lesions and determine optimal choice of therapy.