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Endocrine cancers are a mixed group of diseases characterized by uncontrolled cellular proliferation of the hormone-producing glands of the endocrine system. These include the thyroid, adrenal, pancreas, parathyroid and pituitary glands.
Papillary thyroid cancers (PTC) generally have good prognosis, but their recurrence rate remains high. Here, the authors use proteogenomics and metabolomics to identify molecular features in PTC tumours and determine PTC subtypes that are associated with prognosis and potential targeted therapies.
