Electrocardiography – EKG

Definition

Electrocardiography (EKG or ECG) is a form of diagnostic testing used to monitor the electrical activity of the heart over time via electrodes placed on the skin of the chest. The method can identify aberrant activity caused by heart conditions such as murmurs or myocardial infarction (heart attack).

Latest Research and Reviews

  • Protocols |

    This protocol describes assays for assessing heart rate fluctuations in mice or tissue isolated from mice, including by using in vivo telemetry and in vitro electrophysiology of intact sinoatrial network preparations or isolated single sinoatrial node cells.

    • Stefanie Fenske
    • , Rasmus Pröbstle
    • , Franziska Auer
    • , Sami Hassan
    • , Vanessa Marks
    • , Danius H Pauza
    • , Martin Biel
    •  & Christian Wahl-Schott
    Nature Protocols 11, 61–86
  • Reviews |

    In the past decade, improvements in procedural techniques and the understanding of electrophysiological mechanisms have led to the establishment of effective ablation strategies for almost all types of ventricular tachycardia. The underlying cardiac disease, the site of origin, and the electrophysiological mechanism of the arrhythmia should all be considered when choosing the optimal ablation strategy for an individual patient.

    • Takumi Yamada
    •  & G. Neal Kay
  • Research |

    Nona Sotoodehnia and colleagues report a meta-analysis of 14 genome-wide association studies for QRS interval, an electrocardiogram measurement of cardiac ventricular conduction. They identify 22 loci associated with QRS duration.

    • Nona Sotoodehnia
    • , Aaron Isaacs
    • , Paul I W de Bakker
    • , Marcus Dörr
    • , Christopher Newton-Cheh
    • , Ilja M Nolte
    • , Pim van der Harst
    • , Martina Müller
    • , Mark Eijgelsheim
    • , Alvaro Alonso
    • , Andrew A Hicks
    • , Sandosh Padmanabhan
    • , Caroline Hayward
    • , Albert Vernon Smith
    • , Ozren Polasek
    • , Steven Giovannone
    • , Jingyuan Fu
    • , Jared W Magnani
    • , Kristin D Marciante
    • , Arne Pfeufer
    • , Sina A Gharib
    • , Alexander Teumer
    • , Man Li
    • , Joshua C Bis
    • , Fernando Rivadeneira
    • , Thor Aspelund
    • , Anna Köttgen
    • , Toby Johnson
    • , Kenneth Rice
    • , Mark P S Sie
    • , Ying A Wang
    • , Norman Klopp
    • , Christian Fuchsberger
    • , Sarah H Wild
    • , Irene Mateo Leach
    • , Karol Estrada
    • , Uwe Völker
    • , Alan F Wright
    • , Folkert W Asselbergs
    • , Jiaxiang Qu
    • , Aravinda Chakravarti
    • , Moritz F Sinner
    • , Jan A Kors
    • , Astrid Petersmann
    • , Tamara B Harris
    • , Elsayed Z Soliman
    • , Patricia B Munroe
    • , Bruce M Psaty
    • , Ben A Oostra
    • , L Adrienne Cupples
    • , Siegfried Perz
    • , Rudolf A de Boer
    • , André G Uitterlinden
    • , Henry Völzke
    • , Timothy D Spector
    • , Fang-Yu Liu
    • , Eric Boerwinkle
    • , Anna F Dominiczak
    • , Jerome I Rotter
    • , Gé van Herpen
    • , Daniel Levy
    • , H-Erich Wichmann
    • , Wiek H van Gilst
    • , Jacqueline C M Witteman
    • , Heyo K Kroemer
    • , W H Linda Kao
    • , Susan R Heckbert
    • , Thomas Meitinger
    • , Albert Hofman
    • , Harry Campbell
    • , Aaron R Folsom
    • , Dirk J van Veldhuisen
    • , Christine Schwienbacher
    • , Christopher J O'Donnell
    • , Claudia Beu Volpato
    • , Mark J Caulfield
    • , John M Connell
    • , Lenore Launer
    • , Xiaowen Lu
    • , Lude Franke
    • , Rudolf S N Fehrmann
    • , Gerard te Meerman
    • , Harry J M Groen
    • , Rinse K Weersma
    • , Leonard H van den Berg
    • , Cisca Wijmenga
    • , Roel A Ophoff
    • , Gerjan Navis
    • , Igor Rudan
    • , Harold Snieder
    • , James F Wilson
    • , Peter P Pramstaller
    • , David S Siscovick
    • , Thomas J Wang
    • , Vilmundur Gudnason
    • , Cornelia M van Duijn
    • , Stephan B Felix
    • , Glenn I Fishman
    • , Yalda Jamshidi
    • , Bruno H Ch Stricker
    • , Nilesh J Samani
    • , Stefan Kääb
    •  & Dan E Arking
    Nature Genetics 42, 1068–1076
  • Research |

    Hilma Holm and colleagues report genome-wide association studies to electrocardiographic measures of heart rate, PR interval, QRS duration and QT interval.

    • Hilma Holm
    • , Daniel F Gudbjartsson
    • , David O Arnar
    • , Gudmar Thorleifsson
    • , Gudmundur Thorgeirsson
    • , Hrafnhildur Stefansdottir
    • , Sigurjon A Gudjonsson
    • , Aslaug Jonasdottir
    • , Ellisiv B Mathiesen
    • , Inger Njølstad
    • , Audhild Nyrnes
    • , Tom Wilsgaard
    • , Erin M Hald
    • , Kristian Hveem
    • , Camilla Stoltenberg
    • , Maja-Lisa Løchen
    • , Augustine Kong
    • , Unnur Thorsteinsdottir
    •  & Kari Stefansson
    Nature Genetics 42, 117–122

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