DNA nanotechnology

Definition

DNA nanotechnology is a branch of nanotechnology concerned with the design, study and application of synthetic structures based on DNA. DNA nanotechnology takes advantage of the physical and chemical properties of DNA rather than the genetic information it carries.

Latest Research and Reviews

  • Research |

    Strongly interacting dye molecule complexes with coherent energy transport can be organized through programmable DNA scaffolds.

    • Étienne Boulais
    • , Nicolas P. D. Sawaya
    • , Rémi Veneziano
    • , Alessio Andreoni
    • , James L. Banal
    • , Toru Kondo
    • , Sarthak Mandal
    • , Su Lin
    • , Gabriela S. Schlau-Cohen
    • , Neal W. Woodbury
    • , Hao Yan
    • , Alán Aspuru-Guzik
    •  & Mark Bathe
  • Reviews |

    The field of DNA nanotechnology takes the DNA molecule out of its biological context and uses its information to assemble structural motifs and connect these motifs together. In this Review, a historical account of the field and the approaches used to assemble DNA nanostructures are outlined, followed by a discussion of emerging applications.

    • Nadrian C. Seeman
    •  & Hanadi F. Sleiman
  • Research |

    Primer exchange reaction (PER) cascades have now been used to grow nascent single-stranded DNA with user-specified sequences following prescribed reaction pathways. PER synthesis occurs in a programmable, autonomous, in situ and environmentally responsive fashion, providing a platform for engineering molecular circuits and devices with a wide range of sensing, monitoring, recording, signal processing and actuation capabilities.

    • Jocelyn Y. Kishi
    • , Thomas E. Schaus
    • , Nikhil Gopalkrishnan
    • , Feng Xuan
    •  & Peng Yin
  • Research |

    An approach to form protein-based hydrogels in living cells that resemble physiological hydrogel-like size-dependent molecular sieves is presented. Synthetic RNA granules mimics are obtained by functionalizing these entities with RNA-binding motifs.

    • Hideki Nakamura
    • , Albert A. Lee
    • , Ali Sobhi Afshar
    • , Shigeki Watanabe
    • , Elmer Rho
    • , Shiva Razavi
    • , Allister Suarez
    • , Yu-Chun Lin
    • , Makoto Tanigawa
    • , Brian Huang
    • , Robert DeRose
    • , Diana Bobb
    • , William Hong
    • , Sandra B. Gabelli
    • , John Goutsias
    •  & Takanari Inoue

News and Comment