Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer).
A DNA-based reaction network has now been developed that creates a French flag pattern with immobile and sharp borders from a shallow initial concentration gradient. The output pattern can be used to control the macroscopic organization of DNA-decorated particles thereby inducing a French flag pattern of colloidal aggregation.
Although DNA nanopores are widely explored as synthetic membrane proteins, it is still unclear how the anionic DNA assemblies stably reside within the hydrophobic core of a lipid bilayer. Here, the authors use molecular dynamics simulations to reveal the key dynamic interactions and energetics stabilizing the nanopore-membrane interaction.
MicroRNAs regulate a wide range of biological processes and being able to inhibit their function could allow the development of therapeutic options. Here the authors describe a ‘small RNA zipper’ that sequesters miRNAs by forming a chain of DNA:RNA duplexes.
This month marks ten years since the general principles of DNA origami were established, a technique that changed the field of DNA nanotechnology and that promises new physical and biomedical applications.