Dictyostelium discoideum articles from across Nature Portfolio

Latest Research and Reviews

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  CRISPR/Cas9-based genome-wide screening of Dictyostelium

  • Takanori Ogasawara
  • Jun Watanabe
  • Tetsuya Muramoto

  ResearchOpen Access02 Jul 2022 Scientific Reports

  Volume: 12, P: 11215
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  Phosphorylated Rho–GDP directly activates mTORC2 kinase towards AKT through dimerization with Ras–GTP to regulate cell migration

  Senoo et al. show that, in response to chemoattractant stimulation, phosphorylated Rho–GDP in complex with Ras–GTP and mTORC2 promotes AKT phosphorylation to mediate cell migration.

  • Hiroshi Senoo
  • Yoichiro Kamimura
  • Miho Iijima

  Research01 Jul 2019 Nature Cell Biology

  Volume: 21, P: 867-878
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  Collective cell migration of Dictyostelium without cAMP oscillations at multicellular stages

  Hidenori Hashimura et al. show that cAMP-mediated signaling changes from propagating waves to a steady state at a multicellular stage of amoeba Dictyostelium discoideum. This study suggests that cAMP oscillation is not required for collective cell migration despite its importance at a unicellular stage.

  • Hidenori Hashimura
  • Yusuke V. Morimoto
  • Masahiro Ueda

  ResearchOpen Access24 Jan 2019 Communications Biology

  Volume: 2, P: 34
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  A study of wound repair in Dictyostelium cells by using novel laserporation

  • Mst. Shaela Pervin
  • Go Itoh
  • Shigehiko Yumura

  ResearchOpen Access22 May 2018 Scientific Reports

  Volume: 8, P: 7969
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  The GATA transcription factor GtaC regulates early developmental gene expression dynamics in Dictyostelium

  Development involves dynamic transcriptional changes. By serial ChIP- and RNA-sequencing, here, the authors show that GtaC, a GATA type transcription factor, exhibits temporally distinctive DNA binding and regulation of gene expression concordant with the development in the social amoeba Dictyostelium discoideum.

  • Balaji Santhanam
  • Huaqing Cai
  • Mariko Katoh-Kurasawa

  ResearchOpen Access06 Jul 2015 Nature Communications

  Volume: 6, P: 7551
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  Temporal regulation of kin recognition maintains recognition-cue diversity and suppresses cheating

  It is unclear how variation in cues that enable recognition of kin and facilitate cooperation is maintained. Here, the authors show that rare variants of Dictyostelium discoideumare excluded from aggregates when the potential for social cheating is high, but subsequently rejoin the aggregate and produce spores.

  • Hsing-I Ho
  • Gad Shaulsky

  ResearchOpen Access28 May 2015 Nature Communications

  Volume: 6, P: 7144