CNS cancer

CNS cancer is a type of cancer that forms in the central nervous system. It includes brain stem glioma, craniopharyngioma, medulloblastoma and meningioma.

Latest Research and Reviews

News and Comment

  • Correspondence |

    • Ethan B. Ludmir
    • , Anita Mahajan
    • , Verity Ahern
    • , Thankamma Ajithkumar
    • , Claire Alapetite
    • , Valérie Bernier-Chastagner
    • , Ranjit S. Bindra
    • , Andrew J. Bishop
    • , Stephanie Bolle
    • , Paul D. Brown
    • , Christian Carrie
    • , Anthony J. Chalmers
    • , Eric L. Chang
    • , Caroline Chung
    • , Karin Dieckmann
    • , Natia Esiashvili
    • , Lorenza Gandola
    • , Amol J. Ghia
    • , Vinai Gondi
    • , David R. Grosshans
    • , Semi B. Harrabi
    • , Gail Horan
    • , Danny J. Indelicato
    • , Rakesh Jalali
    • , Geert O. Janssens
    • , Mechthild Krause
    • , Nadia N. Laack
    • , Normand Laperriere
    • , Anne Laprie
    • , Jing Li
    • , Karen J. Marcus
    • , Susan L. McGovern
    • , Thomas E. Merchant
    • , Kenneth W. Merrell
    • , Laetitia Padovani
    • , Jeannette Parkes
    • , Arnold C. Paulino
    • , Rudolf Schwarz
    • , Helen A. Shih
    • , Luis Souhami
    • , Erik P. Sulman
    • , Roger E. Taylor
    • , Nicola Thorp
    • , Beate Timmermann
    • , Greg Wheeler
    • , Suzanne L. Wolden
    • , Kristina D. Woodhouse
    • , Debra N. Yeboa
    • , Torunn I. Yock
    • , Rolf-Dieter Kortmann
    •  & Mary Frances McAleer
  • Correspondence |

    • Kenneth Aldape
    • , Kevin M. Brindle
    • , Louis Chesler
    • , Rajesh Chopra
    • , Amar Gajjar
    • , Mark R. Gilbert
    • , Nicholas Gottardo
    • , David H. Gutmann
    • , Darren Hargrave
    • , Eric C. Holland
    • , David T. W. Jones
    • , Johanna A. Joyce
    • , Pamela Kearns
    • , Mark W. Kieran
    • , Ingo K. Mellinghoff
    • , Melinda Merchant
    • , Stefan M. Pfister
    • , Steven M. Pollard
    • , Vijay Ramaswamy
    • , Jeremy N. Rich
    • , Giles W. Robinson
    • , David H. Rowitch
    • , John H. Sampson
    • , Michael D. Taylor
    • , Paul Workman
    •  & Richard J. Gilbertson
  • News and Views |

    Studies in melanoma and lung cancer indicate that shifting use of immune checkpoint inhibition from palliative stages to the neoadjuvant setting improves response rates and patient outcomes. Three studies now show that neoadjuvant programmed cell death 1 (PD1) inhibition modulates the immune tumour microenvironment — but does this effect translate into a real patient benefit?

    • Anna S. Berghoff
    •  & Matthias Preusser
  • News and Views |

    The cell of origin for malignant brain tumors remains uncertain, but de-differentiation from mature cells in the CNS has always been considered a strong possibility. In this issue of Nature Neuroscience, Alcantara Llaguno and colleagues report that differentiated neurons resist transformation by glioblastoma-associated mutations, pointing to neural stem cells or immature progenitors as the most likely cells of origin for these tumors, rather than cells of a relatively mature neuronal lineage.

    • Peter B. Dirks
    Nature Neuroscience 22, 507-508