Chemistry

Definition

Chemistry is a branch of science that involves the study of the composition, structure and properties of matter. Often known as the central science, it is a creative discipline chiefly concerned with atomic and molecular structure and its change, for instance through chemical reactions.

Featured

Latest Research and Reviews

  • Reviews |

    Advances in biomaterials have enabled control over desired cell responses. Here, the authors highlight key analytical and bioprocessing techniques, outlining a framework for incorporating these tools into designing functionally optimal biomaterials.

    • Max Darnell
    •  & David J. Mooney
    Nature Materials 16, 1178–1185
  • Research |

    A pathway for the production of aromatic amino acid metabolites in Clostridium sporogenes is described; modulation of serum levels of these metabolites in gnotobiotic mice affects intestinal permeability and systemic immunity.

    • Dylan Dodd
    • , Matthew H. Spitzer
    • , William Van Treuren
    • , Bryan D. Merrill
    • , Andrew J. Hryckowian
    • , Steven K. Higginbottom
    • , Anthony Le
    • , Tina M. Cowan
    • , Garry P. Nolan
    • , Michael A. Fischbach
    •  & Justin L. Sonnenburg
  • Research |

    Using a ligand as a promoter enhances the reactivity of the palladium catalyst in non-directed C–H functionalization of arenes, enabling the arene to be used as the limiting reagent.

    • Peng Wang
    • , Pritha Verma
    • , Guoqin Xia
    • , Jun Shi
    • , Jennifer X. Qiao
    • , Shiwei Tao
    • , Peter T. W. Cheng
    • , Michael A. Poss
    • , Marcus E. Farmer
    • , Kap-Sun Yeung
    •  & Jin-Quan Yu
    Nature 551, 489–493
  • Research |

    Cryo-electron microscopy analysis of yeast Rad26 bound to RNA polymerase II provides insight into the initiation of the transcription-coupled DNA repair mechanism in eukaryotes.

    • Jun Xu
    • , Indrajit Lahiri
    • , Wei Wang
    • , Adam Wier
    • , Michael A. Cianfrocco
    • , Jenny Chong
    • , Alissa A. Hare
    • , Peter B. Dervan
    • , Frank DiMaio
    • , Andres E. Leschziner
    •  & Dong Wang
  • Research |

    Ground-based observations during a thunderstorm provide conclusive evidence of positrons being produced after lightning, confirming that lightning can trigger photonuclear reactions.

    • Teruaki Enoto
    • , Yuuki Wada
    • , Yoshihiro Furuta
    • , Kazuhiro Nakazawa
    • , Takayuki Yuasa
    • , Kazufumi Okuda
    • , Kazuo Makishima
    • , Mitsuteru Sato
    • , Yousuke Sato
    • , Toshio Nakano
    • , Daigo Umemoto
    •  & Harufumi Tsuchiya
    Nature 551, 481–484

News and Comment

  • Editorial |

    As the role of biophysical cues in regulating cell behaviour is increasingly understood, more evidence in the field of bioengineering indicates how such signals can affect cells and tissues.

  • News and Views |

    The influence of matrix stiffness and degradation on neural progenitor cell stemness was investigated in a three-dimensional culture system, highlighting the role of remodelling in enhancing cell-to-cell interaction and ultimately maintaining neural stemness.

    • Phillip H. Kang
    • , Sanjay Kumar
    •  & David V. Schaffer
    Nature Materials 16, 1174–1176
  • News and Views |

    Blocking the growth of new blood vessels has been shown to alter fibrosis in livers in a disease stage-specific manner. In vitro models of fibrosis were developed to understand this process, highlighting the role of environmental mechanics.

    • Geoffrey C. Gurtner
    •  & Jagannath Padmanabhan
    Nature Materials 16, 1176–1177
  • Comments and Opinion |

    Biomaterials engineered with specific bioactive ligands, tunable mechanical properties and complex architecture have emerged as powerful tools to probe cell sensing and response to physical properties of their material surroundings, and ultimately provide designer approaches to control cell function.

    • Linqing Li
    • , Jeroen Eyckmans
    •  & Christopher S. Chen
    Nature Materials 16, 1164–1168