Cell vaccines

Cell vaccines are dead or living cells that are used to induce an immune response in the recipient, with the aim of protecting them from future disease or infection.

Latest Research and Reviews

Research | 22 January 2019 | open

A neuraminidase potency assay for quantitative assessment of neuraminidase in influenza vaccines
- Rose T. Byrne-Nash
- , Jacob H. Gillis
- , David F. Miller
- , Katie M. Bueter
- , Laura R. Kuck
- & Kathy L. Rowlen
npj Vaccines 4, 3
Research | 08 October 2018 | open

VaxArray potency assay for rapid assessment of “pandemic” influenza vaccines
- Rose T. Byrne-Nash
- , David F. Miller
- , Katie M. Bueter
- , Jacob H. Gillis
- , Laura R. Kuck
- & Kathy L. Rowlen
npj Vaccines 3, 43
Research | 10 August 2017

Differential transcriptome of tolerogenic versus inflammatory dendritic cells points to modulated T1D genetic risk and enriched immune regulation
- T Nikolic
- , N J C Woittiez
- , A van der Slik
- , S Laban
- , A Joosten
- , C Gysemans
- , C Mathieu
- , J J Zwaginga
- , B Koeleman
- & B O Roep
Genes and Immunity 18, 176-183
Research | 22 May 2017 | open

Notch-mediated conversion of activated T cells into stem cell memory-like T cells for adoptive immunotherapy

Tumour-specific T cells can be expanded in vitro and adoptively transferred for therapy, but this strategy is limited by induction of short-lived T cell populations. Here the authors activate Notch signalling in cultured mouse or human T cells, resulting in the production of a long-lived stem cell memory T cell population that can fight tumours in mice.
- Taisuke Kondo
- , Rimpei Morita
- , Yuumi Okuzono
- , Hiroko Nakatsukasa
- , Takashi Sekiya
- , Shunsuke Chikuma
- , Takashi Shichita
- , Mitsuhiro Kanamori
- , Masato Kubo
- , Keiko Koga
- , Takahiro Miyazaki
- , Yoshiaki Kassai
- & Akihiko Yoshimura
Nature Communications 8, 15338
Research | 07 March 2017 | open

Monitoring of dynamic changes in Keyhole Limpet Hemocyanin (KLH)-specific B cells in KLH-vaccinated cancer patients
- Florian Wimmers
- , Nienke de Haas
- , Anja Scholzen
- , Gerty Schreibelt
- , Elles Simonetti
- , Marc J. Eleveld
- , Huberdina M. L. M. Brouwers
- , Marjo Beldhuis-Valkis
- , Irma Joosten
- , Marien I. de Jonge
- , Winald R. Gerritsen
- , I. Jolanda M. de Vries
- , Dimitri A. Diavatopoulos
- & Joannes F. M. Jacobs
Scientific Reports 7, 43486
Research | 13 February 2017 | open

Interferon-α-inducible Dendritic Cells Matured with OK-432 Exhibit TRAIL and Fas Ligand Pathway-mediated Killer Activity
- Terutsugu Koya
- , Ryu Yanagisawa
- , Yumiko Higuchi
- , Kenji Sano
- & Shigetaka Shimodaira
Scientific Reports 7, 42145

All Research & Reviews

News and Comment

Editorial | 11 June 2018

Towards advanced cell therapies

For cell therapies to transition from promises to products, increased efforts need to be put into the identification of the factors and biological mechanisms that affect safety and efficacy, and into the design of cost-effective methods for the harvesting, expansion, manipulation and purification of the cells.

Nature Biomedical Engineering 2, 339-340
Comments and Opinion | 11 June 2018

Towards superior dendritic-cell vaccines for cancer therapy

Potent dendritic-cell cancer vaccines could be used to induce functional antitumour immunity without off-target toxicity.
- Mansi Saxena
- , Sreekumar Balan
- , Vladimir Roudko
- & Nina Bhardwaj
Nature Biomedical Engineering 2, 341-346
Research Highlights | 30 May 2018

Cancer: Personalized cancer vaccines hit the spot
- Megan Cully
Nature Reviews Drug Discovery 17, 393
Research Highlights | 24 April 2015

Cancer immunotherapy: Primed for a response
- Sarah Seton-Rogers
Nature Reviews Drug Discovery 14, 312
Research Highlights | 02 April 2015

Immunotherapy: Primed for a response

The efficacy of dendritic cell vaccines can be improved in patients with glioblastoma by pre-conditioning the vaccine site with the tetanus/diphtheria toxoid.
- Sarah Seton-Rogers
Nature Reviews Cancer 15, 258-259
News | 07 January 2013

Cell-based vaccines yield only modest advances for seasonal flu
- Cassandra Willyard
Nature Medicine 19, 4

All News & Comment

Cell vaccines

Latest Research and Reviews

News and Comment

Search

Quick links