Cell migration

Cell migration is the process by which cells move from one location to another by adopting different motility modes, such as mesenchymal, amoeboid or collective migration. Cell motility is observed in unicellular organisms, is essential for the development and maintenance of multicellular organisms, and is also involved in immune responses and pathological conditions.

Latest Research and Reviews

News and Comment

  • Research Highlights |

    Having a fever helps T cells reach the site of infection, thanks to thermal sensing by heat shock proteins and induction of integrin-mediated T cell migration.

    • Lucy Bird
  • Research Highlights |

    Two studies from Ashani Weeraratna’s group have examined how changes in the skin microenvironment associated with ageing promote melanoma metastasis and modify immune infiltration.

    • Sarah Seton-Rogers
  • News and Views |

    Classical actin-dependent, integrin-mediated cell–matrix adhesions disassemble before mitotic rounding. Yet, to transmit positional information and facilitate daughter-cell separation, dividing cells maintain connections to the matrix. A previously unidentified class of actin-independent integrin adhesions may fulfil this task.

    • Ronen Zaidel-Bar
    Nature Cell Biology 20, 1233-1235
  • Research Highlights |

    D’Amico et al. show that, in the presence of oncogenic RAS mutations, STAT3 acts as a tumour modifier by regulating the epithelial differentiation of pancreatic and lung cancer cells via p63.

    • Maria Giuseppina Baratta
    Nature Reviews Cancer 18, 664-665