CD4-positive T cells
CD4-positive T cells are a subtype of lymphocyte. They are MHC class II-restricted and are important mediators of adaptive immunity. These cells are involved in both the induction and the restraint of most immunological functions. A key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T cell.
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Reviews | | openExperimental & Molecular Medicine 49, e364
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Research Highlights |Nature Reviews Immunology 17, 403
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